Crystal structures of the trimeric human immunodeficiency virus type 1 matrix protein: Implications for membrane association and assembly

Christopher P. Hill; David Worthylake; Daniel P. Bancroft

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Crystal structures of the trimeric human immunodeficiency virus type 1 matrix protein: Implications for membrane association and assembly

机译：三聚体人类免疫缺陷病毒1型基质蛋白的晶体结构：对膜结合和组装的影响。

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The human immunodeficiency virus type 1 (HIV-1) matrix protein forms a structural shell associated with the inner viral membrane and performs other essential functions throughout the viral life cycle. The crystal structure of the HIV-1 matrix protein, determined at 2.3 A deg resolution, reveals that individual matrix molecules are composed of five major helices capped by a three-stranded mixed β-sheet.

机译：人类免疫缺陷病毒1型（HIV-1）基质蛋白形成与内病毒膜相关的结构壳，并在整个病毒生命周期中执行其他基本功能。 HIV-1基质蛋白的晶体结构在2.3 A deg分辨率下确定，揭示了单个基质分子由五个主要螺旋组成，这些螺旋由三链混合β-折叠覆盖。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第7期|p.3099-3104|共6页
作者
Christopher P. Hill; David Worthylake; Daniel P. Bancroft;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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1. Assembly and release of human immunodeficiency virus type 1 Gag proteins containing tandem repeats of the matrix protein coding sequences in the matrix domain [J] . Wang CT., Chiang CC., Chen SSL. Virology . 2000,第1期

机译：组装和释放人免疫缺陷病毒1型Gag蛋白，在基质结构域中包含基质蛋白编码序列的串联重复
2. Structure of the myristylated human immunodeficiency virus type 2 matrix protein and the role of phosphatidylinositol-(4,5)-bisphosphate in membrane targeting. [J] . Saad JS, Ablan SD, Ghanam RH, Journal of Molecular Biology . 2008,第2期

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3. GB Virus Type C E2 Protein Inhibits Human Immunodeficiency Virus Type 1 Assembly Through Interference With HIV-1 Gag Plasma Membrane Targeting [J] . Christine L Timmons, Qiujia Shao, Chenliang Wang, The Journal of Infectious Diseases . 2013,第7期

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4. Brain-Derived Neurotrophic Factor Prevents Human Immunodeficiency Prevents Human Immunodeficiency Virus Type 1 Protein gp120 Neurotoxicityin the Rat Nigrostriatal System [C] . ITALO MOCCHETTI, RACHEL L. NOSHENY, GIANLUIGI TANDA, International Conference on Neuroprotective Agents: Clinical and Experimental Aspects . 2007

机译：脑衍生的神经营养因子可防止人类免疫缺陷可防止人类免疫缺陷病毒1型蛋白GP120神经毒性素大鼠核心瘤系统
5. Superresolved Three-Dimensional Analysis of the Spatial Arrangement of the Human Immunodeficiency Virus Type-1 (HIV-1) Envelope Glycoprotein at Sites of Viral Assembly [D] . Buttler, Carmen Anne 2018

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6. Crystal structures of the trimeric human immunodeficiency virus type 1 matrix protein: implications for membrane association and assembly. [O] . C P Hill, D Worthylake, D P Bancroft, 1996

机译：三聚体人类免疫缺陷病毒1型基质蛋白的晶体结构：对膜结合和组装的影响。
7. Crystal structures of the trimeric human immunodeficiency virus type 1 matrix protein: implications for membrane association and assembly. [O] . Hill, C P, Worthylake, D, Bancroft, D P, 1996

机译：三聚体人类免疫缺陷病毒1型基质蛋白的晶体结构：对膜结合和组装的影响。
8. C Terminus of Human Immunodeficiency Virus Type 1 Matrix Protein is Involved inEarly Steps of the Virus Life Cycle [R] . Yu, X., Yu, Q. C., Lee, T. H., 1992

机译：人类免疫缺陷病毒1型基质蛋白的C末端参与病毒生命周期的早期步骤

Crystal structures of the trimeric human immunodeficiency virus type 1 matrix protein: Implications for membrane association and assembly

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