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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >P2X_4: An ATP-activated ionotropic receptor cloned from rat brain
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P2X_4: An ATP-activated ionotropic receptor cloned from rat brain

机译:P2X_4:从大鼠大脑克隆的ATP激活的离子受体

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摘要

Extracellular ATP exerts pronounced biolog- ical actions in virtually every organ or tissue that has been studied. In the central and peripheral nervous system, ATP acts as a fast excitatory transmitter in certain synaptic pathways [Evans, R. J., Derkach, V. & Surprenant, A. (1992) Nature (London) 357, 503-505; Edwards, F. A., Gigg, A. J. & Colquhoun, D. (1992) Nature (London) 359, 144-147].
机译:细胞外ATP在几乎所有已研究的器官或组织中都发挥着明显的生物作用。在中枢和周围神经系统中,ATP在某些突触途径中起快速兴奋性递质的作用[Evans,R.J.,Derkach,V。&Surprenant,A。(1992)Nature(London)357,503-505; Engs,1992,Proc.Natl.Acad.Sci。 Edwards,F.A.,Gigg,A.J。&Colquhoun,D。(1992)Nature(London)359,144-147]。

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