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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Assignment of Rfp-Y to the chicken major histocompatibility complex/NOR microchromosome and evidence for high-frequency recombination associated with the nucleolar organizer region
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Assignment of Rfp-Y to the chicken major histocompatibility complex/NOR microchromosome and evidence for high-frequency recombination associated with the nucleolar organizer region

机译:鸡主要组织相容性复合体/ NOR微染色体的Rfp-Y分配以及与核仁组织者区域相关的高频重组的证据

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摘要

Rfp-Y is a second region in the genome of the chicken containing major histocompatibility complex (MHC) class I and II genes. Haplotypes of Rfp-Y assort independently from haplotypes of the B system, a region known to function as a MHC and to be located on chromosome 16 (a microchro- mosome) with the single nucleolar organizer region (NOR) in the chicken genome. Linkage mapping with reference popu- lations failed to reveal the location of Rfp-Y, leaving Rfp-Y unlinked in a map containing >400 markers.
机译:Rfp-Y是鸡基因组中的第二个区域,包含主要的组织相容性复合体(MHC)I和II类基因。 Rfp-Y的单倍型独立于B系统的单倍型,B系统的单倍型已知为MHC,位于鸡基因组中具有单个核仁组织区(NOR)的16号染色体(微染色体)上。与参考人群的连锁图谱未能揭示Rfp-Y的位置,从而使Rfp-Y在包含> 400个标记的图谱中未链接。

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