首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >A loop-loop 'kissing' complex is the essential part of the dimer linkage of genomic HIV-1 RNA
【24h】

A loop-loop 'kissing' complex is the essential part of the dimer linkage of genomic HIV-1 RNA

机译:环状“亲吻”复合物是基因组HIV-1 RNA二聚体连接的重要组成部分

获取原文
获取原文并翻译 | 示例
           

摘要

RNA-RNA interactions govern a number of biological processes. Several RNAs, including natural sense and antisense RNAs, interact by means of a two-step mecha- nism: recognition is mediated by a loop-loop complex, which is then stabilized by formation of an extended intermolecular duplex. It was proposed that the same mechanism holds for dimerization of the genomic RNA of human immunodeficiency virus type 1 (HIV-1), an event thought to control crucial steps of HIV-1 replication.
机译:RNA-RNA相互作用控制着许多生物学过程。几种RNA,包括自然有义和反义RNA,都通过两步机制相互作用:识别由环-环复合物介导,然后通过形成扩展的分子间双链体而稳定下来。有人提出,人类免疫缺陷病毒1型(HIV-1)基因组RNA的二聚化具有相同的机制,该事件被认为可控制HIV-1复制的关键步骤。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号