Inhibition of immunoglobulin folding and secretion by dominant negative BiP ATPase mutants

Linda Hendershot; Jueyang Wei; James Gaut

首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Inhibition of immunoglobulin folding and secretion by dominant negative BiP ATPase mutants

【24h】

Inhibition of immunoglobulin folding and secretion by dominant negative BiP ATPase mutants

机译：显性负BiP ATPase突变体对免疫球蛋白折叠和分泌的抑制

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

A group of resident ER proteins have been identified that are proposed to function as molecular chap- erones. The best characterized of these is BiP/GRP78, an hsp70 homologue that binds peptides containing hydrophobic residues in vitro and unfolded or unassembled proteins in vivo. However, evidence that mammalian BiP plays a direct role in protein folding remains circumstantial.

机译：已经鉴定出一组驻留的ER蛋白，它们被提议作为分子伴侣。其中最有特色的是BiP / GRP78，这是一种hsp70同源物，可在体外结合含有疏水残基的肽和体内未折叠或未装配的蛋白质。但是，哺乳动物BiP在蛋白质折叠中起直接作用的证据仍然是偶然的。

著录项

来源
《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第11期|p.5269-5274|共6页
作者
Linda Hendershot; Jueyang Wei; James Gaut;
展开▼
作者单位

展开▼
收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
关键词

相似文献

外文文献
中文文献
专利

1. An NH2-terminal deleted plasma membrane H+-ATPase is a dominant negative mutant and is sequestered in endoplasmic reticulum derived structures. [J] . Masuda CA, Montero Lomeli-M Biochemistry and Cell Biology . 2000,第1期

机译：NH 2末端缺失的质膜H + -ATPase是一个显性负突变体，被隔离在内质网衍生的结构中。
2. Evidence for a dominant-negative effect in ACTA1 nemaline myopathy caused by abnormal folding, aggregation and altered polymerization of mutant actin isoforms. [J] . Ilkovski B, Nowak KJ, Domazetovska A, Human Molecular Genetics . 2004,第16期

机译：由异常肌动蛋白同工型异常折叠，聚集和聚合反应引起的ACTA1肾病肌病显性负作用的证据。
3. Protein folding and deficiencies caused by dominant-negative mutants of hormones. [J] . Dannies PS Vitamins and hormones. . 2000,第0期

机译：激素的显性负突变体引起的蛋白质折叠和缺陷。
4. Possible involvement of plasma membrane H~+-ATPase in the aluminum-induced secretion of citrate from Arabidopsis roots [C] . H Shen, X. L. Yan, H Matsumoto International Plant Nutrition Colloquium . 2005

机译：质膜H〜+ -ATPase可能参与铝诱导的拟南芥根中柠檬酸的分泌
5. Integrin-cytokine crosstalk and the development of dominant-negative mutants as potential therapeutics [D] . Yu, Jessica. 2015

机译：整联蛋白-细胞因子的串扰和显性负突变体的发展作为潜在的治疗方法
6. Inhibition of immunoglobulin folding and secretion by dominant negative BiP ATPase mutants. [O] . L Hendershot, J Wei, J Gaut, 1996

机译：显性负BiP ATPase突变体对免疫球蛋白折叠和分泌的抑制。
7. Inhibition of immunoglobulin folding and secretion by dominant negative BiP ATPase mutants. [O] . Hendershot, L, Wei, J, Gaut, J, 1996

机译：显性负BiP ATPase突变体对免疫球蛋白折叠和分泌的抑制。

Inhibition of immunoglobulin folding and secretion by dominant negative BiP ATPase mutants

摘要

著录项

相似文献

相关主题

期刊订阅