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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >A novel iron-regulated metal transporter from plants identified by functional expression in yeast
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A novel iron-regulated metal transporter from plants identified by functional expression in yeast

机译:通过在酵母中的功能性表达鉴定的植物中铁调节的新型金属转运蛋白

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摘要

Iron is an essential nutrient for virtually all organisms. The IRT1 (iron-regulated transporter) gene of the plant Arabidopsis thaliana, encoding a probable Fe(II) trans- porter, was cloned by functional expression in a yeast strain defective for iron uptake. Yeast expressing IRT1 possess a novel Fe(II) uptake activity that is strongly inhibited by Cd. IRT1 is predicted to be an integral membrane protein with a metal-binding domain.
机译:铁几乎是所有生物的必需营养素。通过功能性表达将植物拟南芥中的IRT1(铁调节转运蛋白)基因编码为可能的Fe(II)转运蛋白,并将其克隆到对铁吸收有缺陷的酵母菌株中。表达IRT1的酵母具有一种新的Fe(II)摄取活性,该活性被Cd强烈抑制。预计IRT1是具有金属结合域的完整膜蛋白。

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