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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Taste receptor-like cells in the rat gut identified by expression of α-gustducin
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Taste receptor-like cells in the rat gut identified by expression of α-gustducin

机译:通过α-gustducin的表达鉴定大鼠肠中的味觉受体样细胞

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摘要

Theα-subunit of the trimeric G-protein complex specific for taste receptor cells of the tongue, α-gust- ducin, is described here to be also expressed in the stomach and intestine. The α-gustducin-containing cells were identi- fied as brush cells that are scattered throughout the surface epithelium of the gut and share structural features of taste receptor cells of the tongue. These findings provide clues to the long-sought molecular and cellular basis for chemoreception in the gut.
机译:特异于舌头的味觉感受器细胞的三聚体G蛋白复合物的α-亚基,α-gustducducin,在胃和肠中也有表达。含α-gustducin的细胞被鉴定为刷状细胞,它们散布在整个肠道表面上皮中,并具有舌味觉感受器细胞的结构特征。这些发现为肠道化学感受的长期寻找的分子和细胞基础提供了线索。

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