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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Whole body positron emission tomography imaging of simian immunodeficiency virus-infected rhesus macaques
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Whole body positron emission tomography imaging of simian immunodeficiency virus-infected rhesus macaques

机译:猿猴免疫缺陷病毒感染恒河猴的全身正电子发射断层显像

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摘要

Pathogenesis of simian immunodeficiency virus (SIV) infection in rhesus macaques begins with acute viremia and then progresses to a distributed infection in the solid lymphoid tissues, which is followed by a process of cellular destruction leading to terminal disease and death. Blood and tissue specimens show the progress of infection at the cellular level but do not reveal the pattern of infection and host responses occurring throughout the body.
机译:猕猴中猿猴免疫缺陷病毒(SIV)感染的发病机理始于急性病毒血症,然后发展为固态淋巴组织中的分布式感染,随后是细胞破坏的过程,导致终末期疾病和死亡。血液和组织标本在细胞水平上显示了感染的进程,但没有揭示感染的模式和在整个身体中发生的宿主反应。

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