A bacterial artificial chromosome-based framework contig map of human chromosome 22q

Ung-Jin Kim; Hiroaki Shizuya; Hyung-Lyun Kang

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A bacterial artificial chromosome-based framework contig map of human chromosome 22q

机译：基于细菌人工染色体的人类22q染色体框架重叠群图

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We have constructed a physical map of hu- man chromosome 22q using bacterial artificial chromosome (BAC) clones. The map consists of 613 chromosome 22- specific BAC clones that have been localized and assembled into contigs using 452 landmarks, 346 of which were previ- ously ordered and mapped to specific regions of the q arm of the chromosome by means of chromosome 22-specific yeast artificial chromosome clones. The BAC-based map provides immediate access to clones that are stable and convenient for direct genome analysis.

机译：我们使用细菌人工染色体（BAC）克隆构建了人类22q染色体的物理图谱。该图谱由613个22号染色体特异性BAC克隆组成，这些克隆已使用452个地标进行定位并组装成重叠群，其中346个以前被排序，并通过22号染色体特异性映射到了染色体q臂的特定区域。酵母人工染色体克隆。基于BAC的图谱可直接访问稳定且方便直接进行基因组分析的克隆。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第13期|p.6297-6301|共5页
作者
Ung-Jin Kim; Hiroaki Shizuya; Hyung-Lyun Kang;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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正文语种 eng
中图分类自然科学总论;
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1. Comparative Fluorescence in Situ Hybridization Mapping of a 431-kb Arabidopsis thaliana Bacterial Artificial Chromosome Contig Reveals the Role of Chromosomal Duplications in the Expansion of the Brassica rapa Genome [J] . Howard M. Goodman, Jiming Jiang, Ming Li Wang, Genetics: A Periodical Record of Investigations Bearing on Heredity and Variation . 2000,第2期

机译：431-kb拟南芥细菌人工染色体重叠群的比较荧光原位杂交作图揭示了染色体重复在甘蓝型油菜基因组扩展中的作用
2. A yeast artificial chromosome-based physical map of the juvenile amyotrophic lateral sclerosis (ALS2) critical region on human chromosome 2q33-q34. [J] . Hadano S, Nichol K, Brinkman RR, Genomics . 1999,第1期

机译：基于酵母人工染色体的人类染色体2q33-q34上的少年肌萎缩性侧索硬化（ALS2）关键区域的物理图谱。
3. High-level rearrangement and transcription of yeast artificial chromosome-based mouse Ig kappa transgenes containing distal regions of the contig. [J] . Li S, Hammer RE, George Raizen-JB, The Journal of Immunology: Official Journal of the American Association of Immunologists . 2000,第2期

机译：含有重叠群远端区域的基于酵母人工染色体的小鼠Ig kappa转基因的高水平重排和转录。
4. A chromosome-based evaluation model for computer defense immune systems [C] . Zejun Wu, Hongbin Dong, Yiwen Liang, Evolutionary Computation, 2003. CEC '03. The 2003 Congress on . 2003

机译：基于染色体的计算机防御免疫系统评估模型
5. Development of a map-based cloning system in Sorghum bicolor: 1. Isolation of megabase-size DNA and construction of a bacterial artificial chromosome library and 2. Genetic and physical mapping of the 5S rDNA locus. [D] . Woo, Sung-Sick. 1996

机译：双色高粱基于图谱的克隆系统的开发：1.分离碱基大小庞大的DNA和构建细菌人工染色体文库，以及2. 5S rDNA基因座的遗传和物理作图。
6. A bacterial artificial chromosome-based framework contig map of human chromosome 22q. [O] . U J Kim, H Shizuya, H L Kang, 1996

机译：人类染色体22q的基于细菌人工染色体的框架重叠群图。
7. A bacterial artificial chromosome-based framework contig map of human chromosome 22q [O] . Kim Ung-Jin, Shizuya Hiroaki, Kang Hyung-Lyun, 1996

机译：基于细菌人工染色体的人类22q染色体框架重叠群图
8. Human chromosome 21: Linkage mapping and cloning in yeast artificial chromosomes. Progress report. [R] . Antonarakis, S. E. 1991

机译：人类染色体21：酵母人工染色体中的连锁图谱和克隆。进度报告。

A bacterial artificial chromosome-based framework contig map of human chromosome 22q

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