Dopamine inhibits mammalian photoreceptor Na~+,K~+ -ATPase activity via a selective effect on the α3 isozyme

Lanny M. Shulman; Donald A. Fox

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Dopamine inhibits mammalian photoreceptor Na~+,K~+ -ATPase activity via a selective effect on the α3 isozyme

机译：多巴胺通过对α3同工酶的选择性作用抑制哺乳动物的感光细胞Na〜+，K〜+ -ATPase活性

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The rat retina contains dopaminergic inter- plexiform cells that send processes to the outer plexiform layer where dopamine is released in a light-dependent man- ner. We report herein that physiologically relevant concen- trations of dopamine inhibited ouabain-sensitive photorecep- tor oxygen consumption in dark- and light-adapted rat retinas and inhibited Na~+,K~+ -ATPase specific activity (EC 3.6.1.37) in a rat rod outer-inner segment preparation.

机译：大鼠视网膜含有多巴胺能的丛状细胞，该过程将过程发送至外部丛状层，在该层中，多巴胺以光依赖性方式释放。我们在此报告，多巴胺的生理相关浓度在黑暗和光适应的大鼠视网膜中抑制了哇巴因敏感的光感受器氧气消耗，并在大鼠体内抑制了Na〜+，K〜+ -ATPase比活性（EC 3.6.1.37）。大鼠杆内外段的准备。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第15期|p.8034-8039|共6页
作者
Lanny M. Shulman; Donald A. Fox;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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6. Dopamine inhibits mammalian photoreceptor Na+K+-ATPase activity via a selective effect on the alpha3 isozyme. [O] . L M Shulman, D A Fox 1996

机译：多巴胺通过对α3同工酶的选择性作用抑制哺乳动物的感光细胞Na +K + -ATPase活性。
7. Dopamine inhibits mammalian photoreceptor Na+,K+-ATPase activity via a selective effect on the alpha3 isozyme. [O] . Shulman, L M, Fox, D A 1996

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机译：三甲基锡选择性地改变Ca（++），mg（++）和（Ca（++）+ mg（++）） - 人神经母细胞瘤的aTp酶活性

Dopamine inhibits mammalian photoreceptor Na~+,K~+ -ATPase activity via a selective effect on the α3 isozyme

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