Specific accumulation of tumor-derived adhesion factor in tumor blood vessels and in capillary tube-like structures of cultured vascular endothelial cells

Kotaro Akaogi; Yukie Okabe; Junji Sato

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Specific accumulation of tumor-derived adhesion factor in tumor blood vessels and in capillary tube-like structures of cultured vascular endothelial cells

机译：肿瘤来源的粘附因子在肿瘤血管和培养的血管内皮细胞的毛细管样结构中的特异性积累

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Tumor-derived adhesion factor (TAF) was previously identified as a cell adhesion molecule secreted by human bladder carcinoma cell line EJ-1. To elucidate the physiological function of TAF, we examined its distribution in human normal and tumor tissues. Immunochemical staining with an anti-TAF monoclonal antibody showed that TAF was specifically accumulated in small blood vessels and capillaries within and adjacent to tumor nests, but not in those in normal tissues.

机译：肿瘤来源的粘附因子（TAF）先前被鉴定为人膀胱癌细胞系EJ-1分泌的细胞粘附分子。为了阐明TAF的生理功能，我们检查了它在人类正常组织和肿瘤组织中的分布。用抗TAF单克隆抗体进行的免疫化学染色显示，TAF特异性地聚集在肿瘤巢内和邻近的小血管和毛细血管中，而不是在正常组织中。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第16期|p.8384-8389|共6页
作者
Kotaro Akaogi; Yukie Okabe; Junji Sato;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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1. Tumor necrosis factor alpha acts on cultured human vascular endothelial cells to increase the adhesion of pancreatic cancer cells. [J] . Nozawa F, Hirota M, Okabe A, Pancreas . 2000,第4期

机译：肿瘤坏死因子α作用于培养的人血管内皮细胞，以增加胰腺癌细胞的粘附。
2. Distribution of vascular permeability factor (vascular endothelial growth factor) in tumors: concentration in tumor blood vessels. [J] . H F Dvorak, T M Sioussat, L F Brown, The Journal of Experomental Medicine . 1991,第5期

机译：肿瘤中血管通透性因子（血管内皮生长因子）的分布：肿瘤血管中的浓度。
3. Proteolytic cleavage of vascular adhesion protein-1 induced by vascular endothelial growth factor in retinal capillary endothelial cells [J] . Yoshida Shiho, Murata Miyuki, Noda Kousuke, Japanese Journal of Ophthalmology . 2018,第2期

机译：视网膜内皮细胞血管内皮生长因子诱导血管粘附蛋白-1的蛋白水解裂解
4. Mechanical stimulator of cultured vascular endothelial cell for investigation of drug permeability of blood vessel [C] . Shunori A., Shimizu K., Hashida M., The 16th International Conference on olid-State Sensors, Actuators and Microsystems . 2011

机译：机械刺激血管内皮细胞刺激血管的药物渗透性
5. Vascular endothelial growth factor receptor-2 (VEGFR-2) and blood vessel density changes in an experimental model of chronic hydrocephalus . [D] . Deshpande, Abhishek. 2010

机译：慢性脑积水实验模型中血管内皮生长因子受体2（VEGFR-2）和血管密度的变化。
6. Specific accumulation of tumor-derived adhesion factor in tumor blood vessels and in capillary tube-like structures of cultured vascular endothelial cells. [O] . K Akaogi, Y Okabe, J Sato, 1996

机译：肿瘤来源的粘附因子在肿瘤血管和培养的血管内皮细胞的毛细管样结构中的特异性积累。
7. Specific accumulation of tumor-derived adhesion factor in tumor blood vessels and in capillary tube-like structures of cultured vascular endothelial cells. [O] . Akaogi, K, Okabe, Y, Sato, J, 1996

机译：肿瘤来源的粘附因子在肿瘤血管和培养的血管内皮细胞的毛细管样结构中的特异性积累。

Specific accumulation of tumor-derived adhesion factor in tumor blood vessels and in capillary tube-like structures of cultured vascular endothelial cells

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