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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Complex formation between stage-specific oocyte factors and a Xenopus mRNA localization element
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Complex formation between stage-specific oocyte factors and a Xenopus mRNA localization element

机译:阶段特异性卵母细胞因子与非洲爪蟾mRNA定位元件之间的复合物形成

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摘要

It is a long-standing proposal that localiza- tion of maternal factors in eggs can provide the basis for pattern formation in the early embryo. The localized infor- mation can be stored as RNA, one example being Vg1 RNA, which is localized exclusively to the vegetal hemisphere of Xenopus oocytes and eggs. Localization of Vg1 mRNA is directed by a 340-nt sequence element contained within its 3' untranslated region. To understand the mechanism of local- ization, I have tested whether factors from the oocyte interact specifically with the RNA localization sequence.
机译:长期存在的建议是,将卵中的母源因子定位可以为早期胚胎中的模式形成提供基础。本地化信息可以以RNA的形式存储,例如Vg1 RNA,其仅定位于非洲爪蟾卵母细胞和卵的植物半球。 Vg1 mRNA的定位由其3'非翻译区内的340-nt序列元件指导。为了了解定位的机制,我测试了来自卵母细胞的因子是否与RNA定位序列发生特异性相互作用。

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