Mutagenesis associated with nitric oxide production in transgenic SJL mice

Aharon Gal; Gerald N. Wogan

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Mutagenesis associated with nitric oxide production in transgenic SJL mice

机译：转基因SJL小鼠中与一氧化氮产生相关的诱变

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We recently reported development of an ex- perimental model for the study of nitric oxide (NO toxicology in vivo. SJL mice were injected with superantigen-bearing RcsX (pre-B-cell lymphoma) cells, which migrated to the spleen and lymph nodes, where their rapid growth induced activation of macrophages to produce large amounts of NO over a period of several weeks. In the experiments described here, we used this model to investigate mutagenesis in spleno- cytes exposed to NO during RcsX cell growth.

机译：我们最近报道了用于研究一氧化氮（体内NO毒理学）的实验模型的开发。SJL小鼠被注射了带有超抗原的RcsX（前B细胞淋巴瘤）细胞，该细胞迁移至脾脏和淋巴结，在这里描述的实验中，我们使用该模型研究了在RcsX细胞生长过程中暴露于NO的脾细胞中的诱变。

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《Proceedings of the National Academy of Sciences of the United States of America》 |1996年第26期|p.15102-15107|共6页
作者
Aharon Gal; Gerald N. Wogan;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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1. Gender differences of inducible nitric oxide production in SJL/J mice with experimental autoimmune encephalomyelitis. [J] . Ding M, Wong JL, Rogers NE, Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology . 1997,第1期

机译：实验性自身免疫性脑脊髓炎的SJL / J小鼠中诱导型一氧化氮产生的性别差异。
2. Nitric oxide production in SJL mice bearing the RcsX lymphoma: A model for in vivo toxicological evaluation of NO [J] . Aharon Gal, Snait Tamir, Steven R. Tannenbaum Proceedings of the National Academy of Sciences of the United States of America . 1996,第21期

机译：携带RcsX淋巴瘤的SJL小鼠中一氧化氮的产生：NO体内毒理学评估的模型
3. Nitric oxide contributes to the resistance of young SJL/J mice to experimental autoimmune encephalomyelitis. [J] . Staykova MA, Fordham SA, Bartell GJ, Journal of Neuroimmunology: Official Bulletin of the Research Committee on Neuroimmunology of the World Federation of Neurology . 2006,第1a2期

机译：一氧化氮有助于年轻的SJL / J小鼠对实验性自身免疫性脑脊髓炎的抵抗力。
4. Nitric oxide production and inducible nitric oxide synthase induction in iron-loaded rats [C] . T. Kawabata, A. I. Hida, M. Fujisawa, Asia Pacific Electron Paramagnetic Resonance/Electron Spin Resonance Symposium . 2002

机译：铁加载大鼠的一氧化氮产生和诱导型一氧化氮合酶诱导
5. In utero programming of vascular function in transgenic mice lacking endothelial nitric oxide synthase. [D] . Longo, Monica. 2005

机译：在子宫内缺乏血管内一氧化氮合酶的转基因小鼠中血管功能的编程。
6. Mutagenesis associated with nitric oxide production in transgenic SJL mice [O] . Aharon Gal, Gerald N. Wogan 1996

机译：与转基因中一氧化氮产生相关的诱变 SJL老鼠
7. Nitric oxide production in SJL mice bearing the RcsX lymphoma: a model for in vivo toxicological evaluation of NO. [O] . Gal, A, Tamir, S, Tannenbaum, S R, 1996

机译：带有RcsX淋巴瘤的SJL小鼠中一氧化氮的产生：NO体内毒理学评估的模型。

Mutagenesis associated with nitric oxide production in transgenic SJL mice

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