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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Evidence for cross-pathway regulation of metabolic gene expression in plants.
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Evidence for cross-pathway regulation of metabolic gene expression in plants.

机译:植物中代谢基因表达的交叉途径调控的证据。

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摘要

In Arabidopsis thaliana, blocking histidine biosynthesis with a specific inhibitor of imidazoleglycerol-phosphate dehydratase caused increased expression of eight genes involved in the biosynthesis of aromatic amino acids, histidine, lysine, and purines. A decrease in expression of glutamine synthetase was also observed. Addition of histidine eliminated the gene-regulating effects of the inhibitor, demonstrating that the changes in gene expression resulted from histidine-pathway blockage. These results show that plants are capable of cross-pathway metabolic regulation.
机译:在拟南芥中,用咪唑甘油磷酸脱水酶的特异性抑制剂阻断组氨酸的生物合成导致参与芳香族氨基酸,组氨酸,赖氨酸和嘌呤生物合成的八个基因的表达增加。还观察到谷氨酰胺合成酶的表达减少。组氨酸的添加消除了抑制剂的基因调节作用,表明基因表达的变化是由组氨酸途径的阻断引起的。这些结果表明植物能够进行交叉途径的代谢调节。

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