Single-particle EM reveals extensive conformational variability of the Ltn1 E3 ligase

著录项

• 来源
  《Proceedings of the National Academy of Sciences of the United States of America》 |2013年第5期|1702-1707|共6页
• 作者

  Dmitry Lyumkis; Selom K. Doamekpor; Mario H. Bengtson; Joong-Won Lee; Tasha B. Toro; Matthew D. Petroski; Christopher D. Lima; Clinton S. Potter; Bridget Carragher; Claudio A. P. Joazeiro;

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• 作者单位

  National Resource for Automated Molecular Microscopy and Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037;

  Department of Structural Biology, Sloan-Kettering Institute, New York, NY 10065;

  Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037;

  Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037;

  Signal Transduction Program, Sanford-Burnham Medical Research Institute, La Jolla, CA 92037;

  Signal Transduction Program, Sanford-Burnham Medical Research Institute, La Jolla, CA 92037;

  Department of Structural Biology, Sloan-Kettering Institute, New York, NY 10065;

  National Resource for Automated Molecular Microscopy and Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037;

  National Resource for Automated Molecular Microscopy and Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037;

  Department of Cell Biology, The Scripps Research Institute, La Jolla, CA 92037;

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• 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
• 原文格式 PDF
• 正文语种 eng
• 中图分类
• 关键词

  conformational heterogeneity; Ltn1/Listerin; RING E3 ubiquitin ligase; translational surveillance; neurodegenerative disease;

  机译：构象异质性Ltn1 /李斯特林;RING E3泛素连接酶;翻译监督;神经退行性疾病;