Information theory can reveal viral reassortment patterns

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Information theory can reveal viral reassortment patterns

机译：信息论可以揭示病毒的重排模式

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Influenza viruses evolve, in part, via reassortment when different strains infect the same host cell and exchange genetic material. Although these exchanges imprint viral genomes with histories of infections, decoding the information has proven challenging: Just two coinfecting strains, each with a genome consisting of eight segments, represent 256 possible reassortments, Benjamin Green-baum et al. (pp. 3341-3346) propose a method that uses information theory as the mathematical framework for reassortment, revealing insights into the environment that drives these events.

机译：当不同的菌株感染相同的宿主细胞并交换遗传物质时，流感病毒部分地通过重组产生。尽管这些交换会在病毒基因组上留下感染的历史印记，但对信息进行解码却被证明具有挑战性：本杰明·格林鲍姆等人仅将两个共感染菌株（每个基因组由八个片段组成）代表256种可能的重排。（pp。3341-3346）提出了一种使用信息论作为重新分类的数学框架的方法，该方法揭示了驱动这些事件的环境的见解。

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《Proceedings of the National Academy of Sciences of the United States of America》 |2012年第9期|p.3192|共1页
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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Information theory can reveal viral reassortment patterns

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