Chromatin-targeting small molecules cause class-specific transcriptional changes in pancreatic endocrine cells

著录项

• 来源
  《Proceedings of the National Academy of Sciences of the United States of America》 |2012年第14期|p.5364-5369|共6页
• 作者

  Stefan Kubicek; Joshua C. Gilbert; Dina Fomina-Yadlin; Alexander D. Gitlin; Yuan Yuan; Florence F. Wagner; Edward B. Holson; Tuoping Luo; Timothy A. Lewis; Bradley Taylor; Supriya Gupta; Alykhan F. Shamji; Bridget K. Wagner; Paul A. Clemons; Stuart L. Schreiber;

  展开▼
• 作者单位

  Howard Hughes Medical Institute and Cambridge, MA 02142,Broad Institute of Harvard and MIT, Cambridge, MA 02142,CeMM Research Center for Molecular Medicine of the Austrian Academy of Sciences, A-1090 Vienna, Austria;

  Broad Institute of Harvard and MIT, Cambridge, MA 02142;

  Howard Hughes Medical Institute and Cambridge, MA 02142,Broad Institute of Harvard and MIT, Cambridge, MA 02142,Department of Molecular and Cellular Biology and Harvard University, Cambridge, MA 02138;

  Broad Institute of Harvard and MIT, Cambridge, MA 02142,Weill Cornell/Rockefeller/Sloan-Kettering Tri-lnstitutional MD-PhD Program, New York, NY 10065;

  Howard Hughes Medical Institute and Cambridge, MA 02142,Broad Institute of Harvard and MIT, Cambridge, MA 02142,Department of Molecular and Cellular Biology and Harvard University, Cambridge, MA 02138;

  Broad Institute of Harvard and MIT, Cambridge, MA 02142;

  Broad Institute of Harvard and MIT, Cambridge, MA 02142;

  Broad Institute of Harvard and MIT, Cambridge, MA 02142;

  Broad Institute of Harvard and MIT, Cambridge, MA 02142;

  Broad Institute of Harvard and MIT, Cambridge, MA 02142;

  Broad Institute of Harvard and MIT, Cambridge, MA 02142;

  Broad Institute of Harvard and MIT, Cambridge, MA 02142;

  Broad Institute of Harvard and MIT, Cambridge, MA 02142;

  Broad Institute of Harvard and MIT, Cambridge, MA 02142;

  Howard Hughes Medical Institute and Cambridge, MA 02142,Broad Institute of Harvard and MIT, Cambridge, MA 02142,Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138;

  展开▼
• 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
• 原文格式 PDF
• 正文语种 eng
• 中图分类
• 关键词

  histone modification; gene regulation; chemical epigenetics; beta cell biology; cholesterol pathway;

  机译：组蛋白修饰;基因调控;化学表观遗传学β细胞生物学;胆固醇途径;