Dopamine receptor D_3 regulates endocytic sorting by a Prazosin-sensitive interaction with the coatomer COPI

著录项

• 来源
  《Proceedings of the National Academy of Sciences of the United States of America》 |2012年第31期|p.12485-12490|共6页
• 作者

  Xin Zhang; Wenchao Wang; Anne V. Bedigian; Margaret L. Coughlin; Timothy J. Mitchison; Ulrike S. Eggert;

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• 作者单位

  Dana-Farber Cancer Institute,Department of Biological Chemistry and Molecular Pharmacology,High Magnetic Field Laboratory, Chinese Academy of Sciences, Hefei, 230031, People's Republic of China;

  Dana-Farber Cancer Institute,High Magnetic Field Laboratory, Chinese Academy of Sciences, Hefei, 230031, People's Republic of China;

  Dana-Farber Cancer Institute,Department of Biological Chemistry and Molecular Pharmacology, Chinese Academy of Sciences, Hefei, 230031, People's Republic of China;

  Department of Systems Biology, Harvard Medical School, Boston, MA 02115;

  Department of Systems Biology, Harvard Medical School, Boston, MA 02115;

  Dana-Farber Cancer Institute,Department of Biological Chemistry and Molecular Pharmacology,Department of Chemistry and Randall Division of Cell and Molecular Biophysics, King's College London, London SET 1UL, United Kingdom;

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• 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
• 原文格式 PDF
• 正文语种 eng
• 中图分类
• 关键词

  small-molecule inhibitor; endocytic tubulation; unconventional G protein-coupled receptor function; drug off-target effects; membrane trafficking;

  机译：小分子抑制剂内吞管非常规的G蛋白偶联受体功能;药物脱靶效应;膜运输;