首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >A Plasmodium-encoded cytokine suppresses T-cell immunity during malaria
【24h】

A Plasmodium-encoded cytokine suppresses T-cell immunity during malaria

机译:疟原虫编码的细胞因子抑制疟疾期间的T细胞免疫

获取原文
获取原文并翻译 | 示例
           

摘要

The lack of naturally acquired protective immunity to Plasmo-dium parasites is one of the major impediments preventing control of malaria. Adults in malaria-endemic regions develop only partial protection and can be reinfected (1). The ability of memory T cells to confer protection against reinfection by bacteria and viruses.depends on the inflammatory cytokine response (2, 3), but how this response operates in malaria is unknown.
机译:对疟原虫寄生虫缺乏天然获得的保护性免疫是阻止控制疟疾的主要障碍之一。疟疾流行地区的成年人仅能获得部分保护,可以再次感染(1)。记忆性T细胞针对细菌和病毒再感染提供保护的能力取决于炎症性细胞因子反应(2、3),但这种反应如何在疟疾中发挥作用尚不清楚。

著录项

  • 来源
  • 作者单位

    Departments of lnternal Medicine, Yale University School of Medicine, New Haven, CT 06520;

    Departments of lnternal Medicine, Yale University School of Medicine, New Haven, CT 06520;

    Departments of lnternal Medicine, Yale University School of Medicine, New Haven, CT 06520;

    Pharmacology, Yale University School of Medicine, New Haven, CT 06520;

    Departments of lnternal Medicine, Yale University School of Medicine, New Haven, CT 06520;

    Departments of Pharmacology and Systems Therapeutics, Yale University School of Medicine, New Haven, CT 06520;

    Clinical Immunology, Mount Sinai School of Medicine, New York, NY, 10029;

    Departments of lnternal Medicine, Yale University School of Medicine, New Haven, CT 06520;

    Center for Sickle Cell Diseases, Howard University,Washington, DC 20060;

    Malaria Institute at Macha, Choma, Zambia, Howard University,Washington, DC 20060;

    Pharmacology, Yale University School of Medicine, New Haven, CT 06520;

    Leiden Malaria Research Group, Department of Parasitology, Leiden University Medical Centre, 2300 RC, Leiden, The Netherlands;

    Center for Sickle Cell Diseases, Howard University,Washington, DC 20060;

    Leiden Malaria Research Group, Department of Parasitology, Leiden University Medical Centre, 2300 RC, Leiden, The Netherlands;

    Departments of lnternal Medicine, Yale University School of Medicine, New Haven, CT 06520;

  • 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱:kefu@zhangqiaokeyan.com

京公网安备:11010802029741号 ICP备案号:京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有
  • 客服微信

  • 服务号