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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >An unusual phosphatidylethanolamine-utilizing cardiolipin synthase is discovered in bacteria
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An unusual phosphatidylethanolamine-utilizing cardiolipin synthase is discovered in bacteria

机译:在细菌中发现一种不寻常的利用磷脂酰乙醇胺的心磷脂合酶

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摘要

Cardiolipin (also known as diphosphatidylglycerol) is a four-chained anionic membrane phospholipid composed of two phosphatidyl moieties joined by a glycerol link (Fig. 1). It was first isolated from beef heart as a serologically active phospholipid (1), hence the name cardiolipin. In animals, plants, and lower eukaryotic organisms (e.g., yeast), cardiolipin is a component of the inner mitochondrial membrane bilayer, where it plays an important role in the function of enzyme complexes involved in energy transduction and ATP synthesis (2, 3).
机译:心磷脂(也称为二磷脂酰甘油)是一种四链阴离子膜磷脂,由两个通过甘油连接的磷脂酰部分组成(图1)。它首先从牛肉心中分离出来,成为具有血清学活性的磷脂(1),因此称为心磷脂。在动物,植物和低等真核生物(例如酵母)中,心磷脂是内线粒体膜双层的组成部分,在参与能量转导和ATP合成的酶复合体的功能中起着重要作用(2、3) 。

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