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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Mental time travel and default-mode network functional connectivity in the developing brain
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Mental time travel and default-mode network functional connectivity in the developing brain

机译:大脑发育中的心理时间旅行和默认模式网络功能连接

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摘要

A core brain network is engaged in remembering the past and envisioning the future. This network overlaps with the so-called default-mode network, the activity of which increases when demands for focused attention are low. Because of their shared brain substrates, an intriguing hypothesis is that default-mode activity, measured at rest is related to performance in separate attention-focused recall and imagination tasks. However, we do not know how functional connectivity of the default-mode network is related to individual differences in reconstruction of the past and imagination of the future. Here, we show that functional connectivity of the default-mode network in children and adolescents is related to the quality of past remembering and marginally to future imagination. These results corroborate previous findings of a common neuronal substrate for memory and imagination and provide evidence suggesting that mental time travel is modulated by the task-independent functional architecture of the default-mode network in the developing brain. A further analysis showed that local cortical area-lization also contributed to explain recall of the past and imagination of the future, underscoring the benefits of studying both functional and structural properties to understand the brain basis for complex human cognition.
机译:大脑的核心网络致力于回忆过去和展望未来。该网络与所谓的默认模式网络重叠,当对集中注意力的需求较低时,其活动会增加。由于它们共享的大脑底物,一个有趣的假设是,静止时测得的默认模式活动与单独关注注意力的回忆和想象力任务的表现有关。但是,我们不知道默认模式网络的功能连接性如何与过去重构和未来想象力的个体差异相关。在这里,我们表明,儿童和青少年中默认模式网络的功能连接性与过去的记忆质量有关,而与未来的想象力相关。这些结果证实了记忆和想象力的常见神经元底物的先前发现,并提供了证据,表明精神时光的传播受到发育中大脑默认模式网络的与任务无关的功能结构的调节。进一步的分析表明,局部皮质区域的形成也有助于解释过去的回忆和对未来的想象,强调研究功能和结构特性以了解复杂的人类认知的大脑基础的好处。

著录项

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  • 作者单位

    Center for the Study of Human Cognition, Department of Psychology, University of Oslo, 0373 Oslo, Norway;

    Center for the Study of Human Cognition, Department of Psychology, University of Oslo, 0373 Oslo, Norway,Department of Physical Medicine and Rehabilitation, Unit of Neuropsychology, Oslo University Hospital, 0424 Oslo, Norway;

    Center for the Study of Human Cognition, Department of Psychology, University of Oslo, 0373 Oslo, Norway;

    Center for the Study of Human Cognition, Department of Psychology, University of Oslo, 0373 Oslo, Norway;

    Center for the Study of Human Cognition, Department of Psychology, University of Oslo, 0373 Oslo, Norway;

    Center for the Study of Human Cognition, Department of Psychology, University of Oslo, 0373 Oslo, Norway,Department of Physical Medicine and Rehabilitation, Unit of Neuropsychology, Oslo University Hospital, 0424 Oslo, Norway;

  • 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    cortical area; development; fMRI; independent component analysis;

    机译:皮质区域发展;功能磁共振成像;独立成分分析;

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