MicroRNA-15a and -16-1 act via MYB to elevate fetal hemoglobin expression in human trisomy 13

著录项

• 来源
  《Proceedings of the National Academy of Sciences of the United States of America》 |2011年第4期|p.1519-1524|共6页
• 作者

  Vijay G. Sankaran; Tobias F. Menne; Danilo Scepanovic; Jo-Anne Vergilio; Peng Ji; Jinkuk Kim; Prathapan Thiru; Stuart H. Orkin; Eric S. Lander; Harvey F. Lodish;

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• 作者单位

  Whitehead Institute for Biomedical Research, Cambridge, MA 02142 Broad Institute of Massachusetts Institute of Technology and Harvard University,Cambridge, MA 02142 Departments of Medicine and Pathology , Children's Hospital Boston, Boston, MA 02115 Departments of Pediatrics , Harvard Medical School, Boston, MA 02115$11Departments of Systems Biology, Harvard Medical School, Boston, MA 02115;

  Departments of Division of Hematology/Oncology, Children's Hospital Boston, Boston, MA 02115 Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02115;

  Harvard-Massachusetts Institute of Technology Division of Health Sciences and Technology, Cambridge, MA 02142;

  Departments of Pathology , Children's Hospital Boston, Boston, MA 02115;

  Whitehead Institute for Biomedical Research, Cambridge, MA 02142;

  Whitehead Institute for Biomedical Research, Cambridge, MA 02142 Harvard-Massachusetts Institute of Technology Division of Health Sciences and Technology, Cambridge, MA 02142 Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02142;

  Whitehead Institute for Biomedical Research, Cambridge, MA 02142;

  Departments of Pediatrics , Harvard Medical School, Boston, MA 02115 Departments of Division of Hematology/Oncology, Children's Hospital Boston, Boston, MA 02115 Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA 02115 The Howard Hughes Medical Institute, Boston, MA 02115;

  Whitehead Institute for Biomedical Research, Cambridge, MA 02142 Broad Institute of Massachusetts Institute of Technology and Harvard University,Cambridge, MA 02142 Departments of Systems Biology, Harvard Medical School, Boston, MA 02115 Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142;

  Whitehead Institute for Biomedical Research, Cambridge, MA 02142 Broad Institute of Massachusetts Institute of Technology and Harvard University,Cambridge, MA 02142 Department of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142;

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• 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
• 原文格式 PDF
• 正文语种 eng
• 中图分类
• 关键词

  erythropoiesis; globin gene regulation;

  机译：红细胞生成;球蛋白基因调控;