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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >The Arabidopsis thaliana Med25 mediator subunit integrates environmental cues to control plant development
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The Arabidopsis thaliana Med25 mediator subunit integrates environmental cues to control plant development

机译：拟南芥Med25介体亚基整合了环境线索以控制植物发育

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摘要

Development in plants is controlled by abiotic environmental cues such as day length, light quality, temperature, drought, and salinity. These signals are sensed by a variety of systems and trans-' mitted by different signal transduction pathways. Ultimately, these pathways are integrated to control expression of specific target genes, which encode proteins that regulate development and differentiation. The molecular mechanisms for such integration have remained elusive. We here show that a linear 130-amino-acids-long sequence in the Med25 subunit of the Arabidopsis thaliana Mediator is a common target for the drought response element binding protein 2A, zinc finger homeodomain 1, and Myb-like transcription factors which are involved in different stress response pathways. In addition, our results show that Med25 together with drought response element binding protein 2A also function in repression of PhyB-mediated light signaling and thus integrate signals from different regulatory pathways.
机译：植物的发育受非生物环境因素的控制，例如日长，光照质量，温度，干旱和盐度。这些信号由多种系统感测，并由不同的信号转导途径传递。最终，这些途径被整合以控制特定靶基因的表达，该靶基因编码调节发育和分化的蛋白质。这种整合的分子机制仍然难以捉摸。我们在这里显示，拟南芥介体Med25亚基中的线性130个氨基酸长的序列是干旱反应元件结合蛋白2A，锌指同源域1和Myb样转录因子的共同目标在不同的压力反应途径中此外，我们的结果表明，Med25与干旱反应元件结合蛋白2A一起还可以抑制PhyB介导的光信号传导，从而整合来自不同调控途径的信号。

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    Nils Elfving; Celine Davoine; Reyes Benlloch; Jeanette Blomberg; Kristoffer Braennstroem; Doerte Mueller; Anders Nilsson; Mikael Ulfstedt; Hans Ronne; Gunnar Wingsle; Ove Nilsson; Stefan Bjoerklund;

  • 作者单位

    Department of Medical Biochemistry and Biophysics, Umea Plant Science Center, Umea University, SE-901 87 Umea, Sweden;

    Department of Medical Biochemistry and Biophysics, Umea Plant Science Center, Umea University, SE-901 87 Umea, Sweden;

    Department of Forest Genetics and Plant Physiology, Umea Plant Science Center, Swedish University of Agricultural Sciences, 901 83 Umea, Sweden,Centre for Research in Agricultural Genomics, Consorci Consejo Superior de Investigiaciones Cientificas-lnstitut de Recerca i Tecnologia Agroalimentaries-Univer-sitat Autonoma de Barcelona, Bellaterra (Cerdanyola del Valles), 08193 Barcelona, Spain;

    Department of Medical Biochemistry and Biophysics, Umea Plant Science Center, Umea University, SE-901 87 Umea, Sweden;

    Department of Medical Biochemistry and Biophysics, Umea Plant Science Center, Umea University, SE-901 87 Umea, Sweden;

    Department of Biology (Area 11), University of York, P.O. Box 373, York YO10 5YW United Kingdom;

    Department of Microbiology, Swedish University of Agricultural Sciences, Box 7025, SE-75007 Uppsala, Sweden;

    Department of Microbiology, Swedish University of Agricultural Sciences, Box 7025, SE-75007 Uppsala, Sweden;

    Department of Microbiology, Swedish University of Agricultural Sciences, Box 7025, SE-75007 Uppsala, Sweden;

    Department of Forest Genetics and Plant Physiology, Umea Plant Science Center, Swedish University of Agricultural Sciences, 901 83 Umea, Sweden;

    Department of Forest Genetics and Plant Physiology, Umea Plant Science Center, Swedish University of Agricultural Sciences, 901 83 Umea, Sweden;

    Department of Medical Biochemistry and Biophysics, Umea Plant Science Center, Umea University, SE-901 87 Umea, Sweden;

  • 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
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  • 关键词

    transcriptional regulation; phytochro me flowering time 1; RNA polymerase II;

    机译：转录调控;phytochro我开花时间1;RNA聚合酶II;

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