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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Bimodular auxin response controls organogenesis in Arabidopsis
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Bimodular auxin response controls organogenesis in Arabidopsis

机译:双模块生长素反应控制拟南芥中的器官发生。

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摘要

Like animals, the mature plant body develops via successive sets of instructions that determine cell fate, patterning, and organogenesis. In the coordination of various developmental programs, several plant hormones play decisive roles, among which auxin is the best-documented hormonal signal. Despite the broad range of processes influenced by auxin, how such a single signaling molecule can be translated into a multitude of distinct responses remains unclear. In Arabidopsis thaliana, lateral root development is a classic example of a developmental process that is controlled by auxin at multiple stages. Therefore, we used lateral root formation as a model system to gain insight into the multifunctionality of auxin. We were able to demonstrate the complementary and sequential action of two discrete auxin response modules, the previously described SOLITARY ROOT/INDOLE-3-ACETIC ACID (IAA)14-AUXIN REPONSE FACTOR (ARF)7-ARF19-dependent lateral root initiation module and the successive BODENLOS/IAA12-MONOPTEROS/ARF5-dependent module, both of which are required for proper organogenesis. The genetic framework in which two successive auxin response modules control early steps of a developmental process adds an extra dimension to the complexity of auxin's action.
机译:像动物一样,成熟的植物体通过确定细胞命运,模式和器官发生的连续指令集来发育。在各种发育程序的协调中,几种植物激素起着决定性的作用,其中生长素是最有据可查的激素信号。尽管受生长素影响的过程范围很广,但如何将单个信号分子转化为多种不同的反应仍不清楚。在拟南芥中,侧根发育是生长素在多个阶段控制的发育过程的经典实例。因此,我们使用侧根形成作为模型系统来了解生长素的多功能性。我们能够证明两个离散的生长素反应模块的互补和顺序作用,即先前描述的SOLOTARY ROOT / INDOLE-3-ACETIC(IAA)14-AUXIN REPONSE FACTOR(ARF)7-ARF19-dependent横向根起始模块和连续的依赖BODENLOS / IAA12-MONOPTEROS / ARF5的模块,这两个模块都是正常器官发生所必需的。两个连续的生长素应答模块控制发育过程早期步骤的遗传框架为生长素作用的复杂性增加了额外的维度。

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    Department of Plant Systems Biology, Flanders Institute for Biotechnology, B-9052 Ghent, Belgium Department of Plant Biotechnology and Genetics, Ghent University, B-9052 Ghent, Belgium Department of Cell Biology, Max Planck Institute for Developmental Biology, D-72076 Tuebingen, Germany Center for Plant Molecular Biology, University of Tuebingen, D-72076 Tuebingen, Germany;

    Department of Cell Biology, Max Planck Institute for Developmental Biology, D-72076 Tuebingen, Germany Center for Plant Molecular Biology, University of Tuebingen, D-72076 Tuebingen, Germany;

    Center for Plant Molecular Biology, University of Tuebingen, D-72076 Tuebingen, Germany Plant Sciences Division and Centre for Plant Integrative Biology, School of Biosciences, University of Nottingham, Loughborough LE12 5RD, United Kingdom;

    Department of Plant Systems Biology, Flanders Institute for Biotechnology, B-9052 Ghent, Belgium Department of Plant Biotechnology and Genetics, Ghent University, B-9052 Ghent, Belgium;

    Department for Applied Genetics and Cell Biology, University of Natural Resources and Applied Life Sciences, A-1190 Vienna, Austria Department of Molecular Genetics, Faculty of Biology, University of Utrecht, 3584 CH Utrecht, The Netherlands;

    Laboratory of Biochemistry, Wageningen University and Research Centre, 6703 HA Wageningen, The Netherlands;

    Center for Plant Molecular Biology, University of Tuebingen, D-72076 Tuebingen, Germany Syngenta Crop Protection, CH-4332 Stein, Switzerland;

    Department of Plant Systems Biology, Flanders Institute for Biotechnology, B-9052 Ghent, Belgium Department of Plant Biotechnology and Genetics, Ghent University, B-9052 Ghent, Belgium;

    Department of Plant Systems Biology, Flanders Institute for Biotechnology, B-9052 Ghent, Belgium Department of Plant Biotechnology and Genetics, Ghent University, B-9052 Ghent, Belgium M. Popov Institute of Plant Physiology, Bulgarian Academy of Sciences, 1113 Sofia, Bulgaria;

    Department of Plant Systems Biology, Flanders Institute for Biotechnology, B-9052 Ghent, Belgium Department of Plant Biotechnology and Genetics, Ghent University, B-9052 Ghent, Belgium;

    Department of Plant Systems Biology, Flanders Institute for Biotechnology, B-9052 Ghent, Belgium Department of Plant Biotechnology and Genetics, Ghent University, B-9052 Ghent, Belgium;

    Department of Biology and IGSP Center for Systems Biology, Duke University, Durham, NC 27708 Department of Genetics and Genomics, Max Planck Institute for Developmental Biology, D-72076 Tuebingen, Germany;

    Center for Plant Molecular Biology, University of Tuebingen, D-72076 Tuebingen, Germany Lehrstuhl fuer Medizinische Genetik, Universitaet Tubingen, D-72076 Tuebingen, Germany;

    Department of Plant Systems Biology, Flanders Institute for Biotechnology, B-9052 Ghent, Belgium Department of Plant Biotechnology and Genetics, Ghent University, B-9052 Ghent, Belgium;

    Department for Applied Genetics and Cell Biology, University of Natural Resources and Applied Life Sciences, A-1190 Vienna, Austria;

    Department of Biology and IGSP Center for Systems Biology, Duke University, Durham, NC 27708 Center for Plant Molecular Biology, University of Tuebingen, D-72076 Tuebingen, Germany Laboratory of Biochemistry, Wageningen University and Research Centre, 6703 HA Wageningen, The Netherlands;

    Department of Plant Systems Biology, Flanders Institute for Biotechnology, B-9052 Ghent, Belgium Department of Plant Biotechnology and Genetics, Ghent University, B-9052 Ghent, Belgium;

    Plant Sciences Division and Centre for Plant Integrative Biology, School of Biosciences, University of Nottingham, Loughborough LE12 5RD, United Kingdom;

    Department of Cell Biology, Max Planck Institute for Developmental Biology, D-72076 Tuebingen, Germany;

    Center for Plant Molecular Biology, University of Tuebingen, D-72076 Tuebingen, Germany;

    Department of Plant Systems Biology, Flanders Institute for Biotechnology, B-9052 Ghent, Belgium Department of Plant Biotechnology and Genetics, Ghent University, B-9052 Ghent, Belgium;

  • 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    AUXIN/INDOLE-3-ACETIC ACID; AUXIN RESPONSE FACTOR; cell cycle; lateral root;

    机译:AUXIN / INDOLE-3-乙酸AUXIN响应因子;细胞周期;侧根;

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