Mutant Ikzf1 Kras~(G12D), and Notch1 cooperate in T lineage leukemogenesis and modulate responses to targeted agents

著录项

• 来源
  《Proceedings of the National Academy of Sciences of the United States of America》 |2010年第11期|p.5106-5111|共6页
• 作者

  Monique Dail; Qing Li; Andrew McDaniel; Jason Wong; Keiko Akagi; Ben Huang; Hio Chung Kang; Scott C. Kogan; Kevan Shokat; Linda Wolff; Benjamin S. Braun; Kevin Shannon;

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• 作者单位

  Departments of Pediatrics, University of California, San Francisco, CA 94143;

  rnDepartments of Medicine, University of California, San Francisco, CA 94143;

  rnDepartments of Pediatrics, University of California, San Francisco, CA 94143;

  rnDepartments of Pediatrics, University of California, San Francisco, CA 94143;

  rnDepartment of Molecular Virology, Immunology, and Medical Genetics, Ohio State University, Columbus, OH 43210;

  rnDepartments of Pediatrics, University of California, San Francisco, CA 94143;

  rnDepartments of Pediatrics, University of California, San Francisco, CA 94143;

  rnDepartments of Laboratory Medicine, University of California, San Francisco, CA 94143;

  rnDepartments of Pharmaceutical Chemistry, University of California, San Francisco, CA 94143;

  rnLaboratory of Cellular Oncology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892;

  rnDepartments of Pediatrics, University of California, San Francisco, CA 94143;

  rnDepartments of Pediatrics, University of California, San Francisco, CA 94143;

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• 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
• 原文格式 PDF
• 正文语种 eng
• 中图分类
• 关键词

  K-ras; retroviral insertional mutagenesis; T cell leukemia; targeted therapeutics; Ikaros;

  机译：K-ras;逆转录病毒插入诱变;T细胞白血病;靶向治疗;伊卡罗斯;