Preclinical vascular disease identifies smokers at risk for COPD

James D. Crapo

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Preclinical vascular disease identifies smokers at risk for COPD

机译：临床前血管疾病确定吸烟者有COPD风险

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Chronic obstructive pulmonary disease (COPD) is the only disease among the 10 leading causes of death in the United States with a prevalence that has steadily increased over the past four decades and for which no effective therapy has been developed to substantially blunt its progressive course. COPD has climbed to become the fourth leading cause of death in the United States, leading to the deaths of more than 120,000 people each year. Healthcare expenses and loss of work because of this disease have been estimated to cost over $37 billion annually. COPD is traditionally identified by the finding of an irreversible chronic airflow limitation. This limitation is thought to be present (diagnosed and undiagnosed) in up to 50 million people in the United States (1).

机译：慢性阻塞性肺疾病（COPD）是美国十大主要死因中唯一的一种疾病，其发病率在过去四十年中一直稳定增长，并且尚未开发出有效的治疗方法来显着抑制其进展进程。 COPD已攀升成为美国第四大死亡原因，每年导致超过12万人死亡。据估计，由于这种疾病，医疗保健费用和工作损失每年造成的费用超过370亿美元。传统上，通过发现不可逆的慢性气流受限来确定COPD。在美国，这一限制被认为存在于（诊断和未诊断的）多达五千万人中（1）。

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《Proceedings of the National Academy of Sciences of the United States of America》 |2010年第19期|P.8503-8504|共2页
作者
James D. Crapo;
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作者单位

Department of Medicine, National Jewish Health, Denver, CO 80206;

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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
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正文语种 eng
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Preclinical vascular disease identifies smokers at risk for COPD

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