Working toward a synthesis of archaeological,linguistic, and genetic data for inferring African population history

Laura B. Scheinfeldt; rnSameer Soi; rnSarah A. Tishkoff

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Working toward a synthesis of archaeological,linguistic, and genetic data for inferring African population history

机译：致力于综合考古，语言和遗传数据以推断非洲人口历史

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Although Africa is the origin of modern humans, the pattern and distribution of genetic variation and correlations with cultural and linguistic diversity in Africa have been understudied. Recent advances in genomic technology, however, have led to genomewide studies of African samples. In this article, we discuss genetic variation in African populations contextualized with what is known about archaeological and linguistic variation. What emerges from this review is the importance of using independent lines of evidence in the interpretation of genetic and genomic data in the reconstruction of past population histories.

机译：尽管非洲是现代人类的起源，但人们仍在研究遗传变异的模式和分布以及与非洲文化和语言多样性的相关性。然而，基因组技术的最新进展已导致对非洲样品进行全基因组研究。在本文中，我们将讨论有关考古和语言变异的背景下非洲人口的遗传变异。从这篇评论中得出的是，在重建过去的人口历史中，在解释遗传和基因组数据时使用独立的证据是很重要的。

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《Proceedings of the National Academy of Sciences of the United States of America》 |2010年第2期|P.8931-8938|共8页
作者
Laura B. Scheinfeldt; rnSameer Soi; rnSarah A. Tishkoff;
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作者单位

Department of Genetics,University of Pennsylvania, Philadelphia, PA 19104;

rnGenomics and Computational Biology Graduate Group, University of Pennsylvania, Philadelphia, PA 19104;

rnDepartment of Biology, University of Pennsylvania, Philadelphia, PA 19104;

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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类
关键词
genetic variation; human evolution; mitochondria; DNA;

机译：遗传变异;人类进化线粒体脱氧核糖核酸;

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1. Population history and gene dispersal inferred from spatial genetic structure of a Central African timber tree, Distemonanthus benthamianus (Caesalpinioideae). [J] . Debout GD, Doucet JL, Hardy OJ Heredity: An International Journal of Genetics . 2011,第1期

机译：从中部非洲木本植物Distemonanthus benthamianus（Caesalpinioideae）的空间遗传结构推断出种群历史和基因扩散。
2. Small-scale spatial genetic structure in the Central African rainforest tree species Aucoumea klaineana: a stepwise approach to infer the impact of limited gene dispersal, population history and habitat fragmentation [J] . Born C, Hardy OJ, Chevallier MH, Molecular ecology . 2008,第8期

机译：中部非洲雨林树种Aucoumea klaineana的小规模空间遗传结构：一种逐步方法来推断有限的基因扩散，种群历史和栖息地破碎化的影响
3. Southeast Asian origins of five Hill Tribe populations and correlation of genetic to linguistic relationships inferred with genome-wide SNP data [J] . Listman J.B., Malison R.T., Sanichwankul K., American Journal of Physical Anthropology . 2011,第2期

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4. An Integrated Analysis of Genome-Wide DNA Methylation and Genetic Variants Underlying Etoposide-Induced Cytotoxicity in European and African Populations [C] . Ruowang Li, Dokyoon Kim, Scott M. Dudek, European conference on applications of evolutionary computation . 2014

机译：对欧洲和非洲人口中依托泊苷诱导的细胞毒作用的全基因组DNA甲基化和遗传变异的综合分析
5. Model-based population genetics in indigenous humans: Inferences of demographic history, adaptive selection, and African archaic admixture using whole-genome/exome sequencing data [D] . Hsieh, PingHsun. 2016

机译：土着人群中基于模型的人口遗传学：使用全基因组/外壳测序数据的人口历史，自适应选择和非洲古代混合物的推论
6. Colloquium Paper: Working toward a synthesis of archaeological linguistic and genetic data for inferring African population history [O] . Laura B. Scheinfeldt, Sameer Soi, Sarah A. Tishkoff 2010

机译：讨论会论文：致力于综合考古语言和遗传数据以推断非洲人口历史
7. Working toward a synthesis of archaeological, linguistic, and genetic data for inferring African population history [O] . Scheinfeldt, Laura B., Soi, Sameer, Tishkoff, Sarah A. 2010

机译：致力于综合考古，语言和遗传数据以推断非洲人口历史

Working toward a synthesis of archaeological,linguistic, and genetic data for inferring African population history

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