RBX1/R0C1 disruption results in early embryonic lethality due to proliferation failure, partially rescued by simultaneous loss of p27

著录项

• 来源
  《Proceedings of the National Academy of Sciences of the United States of America》 |2009年第15期|6203-6208|共6页
• 作者

  Mingjia Tan; Shannon W. Davis; Thomas L. Saunders; Yuan Zhu; Yi Sun;

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• 作者单位

  Division of Radiation and Cancer Biology, Department of Radiation Oncology, University of Michigan Comprehensive Cancer Center, 4424B MS I, 1301 Catherine Street, Ann Arbor, Ml 48109-5936;

  Department of Human Genetics, 4909 Buhl SPC 5618, University of Michigan Medical School, Ann Arbor, Ml 48109-0669;

  Division of Molecular Medicine and Genetics, Department of Internal Medicine, Transgenic Animal Model Core, Biomedical Research Core Facilities, 2570 MSRB II, SRC 5674, University of Michigan Medical School, Ann Arbor, Ml 48109-0618;

  Division of Molecular Medicine and Genetics, Departments of Internal Medicine and Cell and Developmental Biology, University of Michigan Medical School, 2061 BSRB, 109 Zina Pitcher, Ann Arbor, Ml 48109-2200;

  Division of Radiation and Cancer Biology, Department of Radiation Oncology, University of Michigan Comprehensive Cancer Center, 4424B MS I, 1301 Catherine Street, Ann Arbor, Ml 48109-5936;

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• 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
• 原文格式 PDF
• 正文语种 eng
• 中图分类
• 关键词

  SCF E3 ubiquitin ligase; protein degradation; growth suppression;

  机译：SCF E3泛素连接酶;蛋白质降解;生长抑制;