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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Neural activity in the visual thalamus reflects perceptual suppression
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Neural activity in the visual thalamus reflects perceptual suppression

机译:视觉丘脑中的神经活动反映了知觉抑制

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摘要

To examine the role of the visual thalamus in perception, we recorded neural activity in the lateral geniculate nucleus (LGN) and pulvinar of 2 macaque monkeys during a visual illusion that induced the intermittent perceptual suppression of a bright luminance patch. Neural responses were sorted on the basis of the trial-to-trial visibility of the stimulus, as reported by the animals. We found that neurons in the dorsal and ventral pulvinar, but not the LGN, showed changes in spiking rate according to stimulus visibility. Passive viewing control sessions showed such modulation to be independent of the monkeys' active report. Perceptual suppression was also accompanied by a marked drop in low-frequency power (9-30 Hz) of the local field potential (LFP) throughout the visual thalamus, but this modulation was not observed during passive viewing. Our findings demonstrate that visual responses of pulvinar neurons reflect the perceptual awareness of a stimulus, while those of LGN neurons do not.
机译:为了检查视觉丘脑在感知中的作用,我们在视觉错觉期间记录了两只猕猴的外侧膝状核(LGN)和肺泡的神经活动,该视觉错觉导致间歇性知觉抑制明亮的亮度斑块。如动物报告的那样,根据刺激的试验可见性对神经反应进行分类。我们发现,根据刺激可见度,背侧和腹侧神经元的神经元(而非LGN)显示出刺突率的变化。被动观看控制会话显示这种调制独立于猴子的主动报告。在整个视觉丘脑中,知觉抑制还伴随着局部场电势(LFP)的低频功率(9-30 Hz)的显着下降,但在被动观察过程中未观察到这种调制。我们的研究结果表明,鼓神经元的视觉反应反映了刺激的知觉意识,而LGN神经元的视觉反应却没有。

著录项

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  • 作者单位

    Unit on Cognitive Neurophysiology and Imaging, Laboratory of Neuropsychology, National Institute of Mental Health, National Institutes of Health, Building 49, Room B2J-45, MSC-4400 49 Convent Drive, Bethesda, MD 20892 Division of Biology, California Institute of Technology, Pasadena, CA91125;

    Unit on Cognitive Neurophysiology and Imaging, Laboratory of Neuropsychology, National Institute of Mental Health, National Institutes of Health, Building 49, Room B2J-45, MSC-4400 49 Convent Drive, Bethesda, MD 20892 lntemational Max Planck Research School, University of Tuebingen, Oesterbergstrasse 3, D-72074 Tuebingen, Germany;

    Unit on Cognitive Neurophysiology and Imaging, Laboratory of Neuropsychology, National Institute of Mental Health, National Institutes of Health, Building 49, Room B2J-45, MSC-4400 49 Convent Drive, Bethesda, MD 20892 Neurophysiology Imaging Facility, National Institute of Mental Health, National Institute of Neurological Disorders and Stroke, National Eye Institute, National Institutes of Health, Building 49, Room B2J-45, MSC-4400 49 Convent Drive, Bethesda, MD 20892;

  • 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

    vision; LGN; awareness; pulvinar; attention;

    机译:视力;LGN;意识;ul注意;

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