Alternative splicing of the G protein-coupled receptor superfamily in human airway smooth muscle diversifies the complement of receptors

Richard Einstein; Heather Jordan; Weiyin Zhou; Michael Brenner; Esther G. Moses; Stephen B. Liggett

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Alternative splicing of the G protein-coupled receptor superfamily in human airway smooth muscle diversifies the complement of receptors

机译：G蛋白偶联受体超家族在人气道平滑肌中的可变剪接使受体的补体多样化

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G protein-coupled receptors (GPCRs) are the largest signaling family in the genome, serve an expansive array of functions, and are targets for 50% of current therapeutics. In many tissues, such as airway smooth muscle (ASM), complex, unexpected, or parado

机译：G蛋白偶联受体（GPCR）是基因组中最大的信号转导家族，具有广泛的功能，是50％当前治疗药物的靶标。在许多组织中，例如气道平滑肌（ASM），复杂，意外或天堂

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《Proceedings of the National Academy of Sciences of the United States of America》 |2008年第13期|5230-5235|共6页
作者
Richard Einstein; Heather Jordan; Weiyin Zhou; Michael Brenner; Esther G. Moses; Stephen B. Liggett;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
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关键词
pharmacogenetics; signal transduction; splice variants;

机译：药物遗传学信号转导;剪接变体;

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1. Cooperative Regulation of p70S6 Kinase by Receptor Tyrosine Kinases and G Protein-Coupled Receptors Augments Airway Smooth Muscle Growth [J] . Charlotte K.Billington, Kok C.Kong, Raja Bhattacharyya, Biochemistry . 2005,第44期

机译：受体酪氨酸激酶和G蛋白偶联受体增强气道平滑肌生长对p70S6激酶的协同调节
2. Human Airway Smooth Muscle Cells Express the High Affinity Receptor for IgE (FcεRI): A Critical Role of FcεRI in Human Airway Smooth Muscle Cell Function [J] . Abdelilah Soussi Gounni, Vincent Wellemans, Jia Yang, The journal of immunology . 2005,第4期

机译：人气道平滑肌细胞表达IgE（FcεRI）的高亲和力受体：FcεRI在人气道平滑肌细胞功能中的关键作用
3. Human Airway Smooth Muscle Cells Express the High Affinity Receptor for IgE (Fc{epsilon}RI): A Critical Role of Fc{epsilon}RI in Human Airway Smooth Muscle Cell Function. [J] . Gounni AS, Wellemans V, Yang J, The Journal of Immunology: Official Journal of the American Association of Immunologists . 2005,第4期

机译：人气道平滑肌细胞表达IgE（FcεRI）的高亲和力受体：FcεepsRI在人气道平滑肌细胞功能中的关键作用。
4. Mutations in G proteins and G protein-coupled receptors in human endocrine diseases [C] . Allen Spiege Colloque me?decine et recherche . 2006

机译：在人内分泌疾病中G蛋白和G蛋白偶联受体中的突变
5. Molecular Regulation and Effector Functions of the High Affinity IgE Receptor (FcepsilonRI) in Human Airway Smooth Muscle Cells. [D] . Redhu, Naresh Singh. 2012

机译：高亲和力IgE受体（FcepsilonRI）在人气道平滑肌细胞中的分子调控和效应子功能。
6. Alternative splicing of the G protein-coupled receptor superfamily in human airway smooth muscle diversifies the complement of receptors [O] . Richard Einstein, Heather Jordan, Weiyin Zhou, 2008

机译：G蛋白偶联受体超家族在人气道平滑肌中的可变剪接使受体的补体多样化
7. Alternative splicing of the G protein-coupled receptor superfamily in human airway smooth muscle diversifies the complement of receptors [O] . Einstein, Richard, Jordan, Heather, Zhou, Weiyin, 2008

机译：G蛋白偶联受体超家族在人气道平滑肌中的可变剪接使受体的补体多样化

Alternative splicing of the G protein-coupled receptor superfamily in human airway smooth muscle diversifies the complement of receptors

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