MicroRNA-repressed mRNAs contain 40S but not 60S components

Bingbing Wang; Adrienne Yanez; Carl D. Novina

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MicroRNA-repressed mRNAs contain 40S but not 60S components

机译：抑制MicroRNA的mRNA包含40S但不包含60S成分

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MicroRNAs (miRNAs) are small noncoding RNAs that may target more than one-third of human genes, yet the mechanisms used by miRNAs to repress translation of target mRNAs are obscure. Using a recently described cell-free assay of miRNA function, we observe

机译：微小RNA（miRNA）是小的非编码RNA，可以靶向超过三分之一的人类基因，但miRNA用来抑制目标mRNA的翻译的机制尚不清楚。使用最近描述的miRNA功能的无细胞检测，我们观察到

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《Proceedings of the National Academy of Sciences of the United States of America》 |2008年第14期|5343-5348|共6页
作者
Bingbing Wang; Adrienne Yanez; Carl D. Novina;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
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关键词
argonaute; translation; ribosome;

机译：精子翻译;核糖体;

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专利

1. Myb-Related Fission Yeast cdc5p Is a Component of a 40S snRNP-Containing Complex and Is Essential for Pre-mRNA Splicing [J] . W. Hayes McDonald, Ryoma Ohi, Natalia Smelkova, Molecular and Cellular Biology . 1999,第8期

机译：与Myb相关的裂变酵母cdc5p是40S snRNP含有复合物的组成部分，是mRNA剪接前所必需的
2. Latency differences of N20, P40/N60, P100/N140 SEP components after stimulation of proximal and distal sites of the median nerve. [J] . Hada Y Clinical EEG and neuroscience: official journal of the EEG and Clinical Neuroscience Society (ENCS) . 2006,第1期

机译：N20，P40 / N60，P100 / N140 SEP组件在刺激正中神经的近端和远端后的延迟差异。
3. The DEAD-box Protein Rok1 Orchestrates 40S and 60S Ribosome Assembly by Promoting the Release of Rrp5 from Pre-40S Ribosomes to Allow for 60S Maturation [J] . Sohail Khoshnevis, Isabel Askenasy, Matthew C. Johnson, PLoS Biology . 2016,第6期

机译：DEAD盒蛋白Rok1通过促进从40S以前的核糖体释放Rrp5到60S成熟来协调40S和60S核糖体装配。
4. Neuronal P-bodies and Transport of microRNA-Repressed mRNAs [C] . Florence Rage Colloque me?decine et recherche . 2010

机译：神经元p-体和微小荷载MRNA的运输
5. Recruitment of the ribosomal 40S subunit to the 3'untranslated region of a viral mRNA, via the eIF4 complex, facilitates cap-independent translation. [D] . Sharma, Sohani Das. 2014

机译：经由eIF4复合物将核糖体40S亚基募集至病毒mRNA的3'非翻译区，促进了不依赖于帽的翻译。
6. MicroRNA-repressed mRNAs contain 40S but not 60S components [O] . Bingbing Wang, Adrienne Yanez, Carl D. Novina 2008

机译：抑制MicroRNA的mRNA包含40S但不包含60S成分
7. MicroRNA-repressed mRNAs contain 40S but not 60S components [O] . Wang, Bingbing, Yanez, Adrienne, Novina, Carl D. 2008

机译：抑制MicroRNA的mRNA包含40S但不包含60S成分

MicroRNA-repressed mRNAs contain 40S but not 60S components

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