Small-molecule RETRA suppresses mutant p53-bearing cancer cells through a p73-dependent salvage pathway

J. E. Kravchenko; G. V. Ilyinskaya; P. G. Komarov; L. S. Agapova; D. V. Kochetkov; E. Strom; E. I. Frolova; I. Kovriga; A. V. Gudkov; E. Feinstein; P. M. Chumakov

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Small-molecule RETRA suppresses mutant p53-bearing cancer cells through a p73-dependent salvage pathway

机译：小分子RETRA通过依赖p73的挽救途径抑制携带p53的癌细胞

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Identification of unique features of cancer cells is important for defining specific and efficient therapeutic targets. Mutant p53 is present in nearly half of all cancer cases, forming a promising target for pharmacological reactivation. In addition to b

机译：癌细胞独特特征的鉴定对于定义特异性和有效的治疗靶标很重要。 p53突变体存在于所有癌症病例的近一半中，形成了有希望的药理学活化靶标。除了b

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《Proceedings of the National Academy of Sciences of the United States of America》 |2008年第17期|6302-6307|共6页
作者
J. E. Kravchenko; G. V. Ilyinskaya; P. G. Komarov; L. S. Agapova; D. V. Kochetkov; E. Strom; E. I. Frolova; I. Kovriga; A. V. Gudkov; E. Feinstein; P. M. Chumakov;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
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关键词
cancer therapy; p73 family; tumor suppressors;

机译：癌症治疗;p73家庭;肿瘤抑制剂;

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6. Small-molecule RETRA suppresses mutant p53-bearing cancer cells through a p73-dependent salvage pathway [O] . J. E. Kravchenko, G. V. Ilyinskaya, P. G. Komarov, 2008

机译：小分子RETRA通过依赖p73的挽救途径抑制携带p53的癌细胞
7. Small-molecule RETRA suppresses mutant p53-bearing cancer cells through a p73-dependent salvage pathway [O] . Kravchenko, J. E., Ilyinskaya, G. V., Komarov, P. G., 2008

机译：小分子RETRA通过依赖p73的挽救途径抑制携带p53的癌细胞

Small-molecule RETRA suppresses mutant p53-bearing cancer cells through a p73-dependent salvage pathway

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