Structural basis for tropomyosin overlap in thin (actin) filaments and the generation of a molecular swivel by troponin-T

Kenji Murakami; Murray Steward; Kayo Nozawa; Kumiko Tomii; Norio Kudou; Noriyuki Igarashi; Yasuo Shirakihara; Soichi Wakatsuki; Takuo Yasunaga; Takeyuki Wakabayashi

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Structural basis for tropomyosin overlap in thin (actin) filaments and the generation of a molecular swivel by troponin-T

机译：原肌动蛋白在细丝（肌动蛋白）细丝中重叠的结构基础以及肌钙蛋白-T产生分子旋转体

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Head-to-tail polymerization of tropomyosin is crucial for its act in binding, function in actin filament assembly, and the regulation of actin-myosin contraction. Here, we describe the 2.1 A resolution structure of crystals containing overlapping tropomyo

机译：原肌球蛋白的从头到尾聚合对于其在结合中的作用，在肌动蛋白丝装配中的功能以及肌动蛋白-肌球蛋白收缩的调节至关重要。在这里，我们描述2.1 A包含重叠的原肌球的晶体的分辨结构

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《Proceedings of the National Academy of Sciences of the United States of America》 |2008年第20期|7200-7205|共6页
作者
Kenji Murakami; Murray Steward; Kayo Nozawa; Kumiko Tomii; Norio Kudou; Noriyuki Igarashi; Yasuo Shirakihara; Soichi Wakatsuki; Takuo Yasunaga; Takeyuki Wakabayashi;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类
关键词
calcium; cardiomyopathy; troponin;

机译：钙;心肌病;肌钙蛋白;

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专利

1. The structural dynamics of a-tropomyosin on F-actin shape the overlap complex between adjacent tropomyosin molecules [J] . William Lehman, Xiaochuan (Edward) Li, Marek Orzechowski, Archives of Biochemistry and Biophysics . 2014,第Null期

机译：a-原肌球蛋白在F-肌动蛋白上的结构动力学形成相邻原肌球蛋白分子之间的重叠复合体
2. Actin-tropomyosin activation of myosin subfragment 1 ATPase and thin filament cooperativity. The role of tropomyosin flexibility and end-to-end interactions [J] . Lehrer SS, Golitsina NL, Geeves MA Biochemistry . 1997,第44期

机译：肌动蛋白原肌球蛋白激活肌球蛋白亚片段1 ATPase和细丝协同作用。原肌球蛋白灵活性和端对端相互作用的作用
3. Actin, alpha-actinin, and tropomyosin interaction in the structural organization of actin filaments in nonmuscle cells. [J] . E Lazarides Journal of cell biology . 1976,第2期

机译：非肌肉细胞中肌动蛋白丝的结构组织中的肌动蛋白，α-肌动蛋白和原肌球蛋白相互作用。
4. Tropomyosin rotational dynamics in thin filaments [C] . Jun-chih Lo, Richard D. Ludescher Fluorescence Science and Technology . 2000

机译：薄纱中的ropomyosin旋转动力学
5. Deciphering the Tropomyosin Code: Uncovering How Different Tropomyosin Isoforms Bind and Assemble on Actin Filaments [D] . ?Rodriguez, Johnny 2020

机译：破译原猪代码：揭示不同的原鸡同种型如何在肌动蛋白长丝上结合和组装
6. Structural basis for tropomyosin overlap in thin (actin) filaments and the generation of a molecular swivel by troponin-T [O] . Kenji Murakami, Murray Stewart, Kayo Nozawa, 2008

机译：原肌动蛋白在细丝（肌动蛋白）细丝中重叠的结构基础以及肌钙蛋白-T产生分子旋转体
7. Structural basis for tropomyosin overlap in thin (actin) filaments and the generation of a molecular swivel by troponin-T [O] . Murakami, Kenji, Stewart, Murray, Nozawa, Kayo, 2008

机译：原肌动蛋白在细丝（肌动蛋白）细丝中重叠的结构基础以及肌钙蛋白-T产生分子旋转体

Structural basis for tropomyosin overlap in thin (actin) filaments and the generation of a molecular swivel by troponin-T

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