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Properties Of Developmental Gene Regulatory Networks

机译:发育基因调控网络的特性

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摘要

The modular components, or subcircuits, of developmental gene regulatory networks (GRNs) execute specific developmental functions, such as the specification of cell identity. We survey examples of such subcircuits and relate their structures to corresponding developmental functions. These relations transcend organisms and genes, as illustrated by the similar structures of the subcircuits controlling the specification of the mesectoderm in the Drosophila embryo and the endomesoderm in the sea urchin, even though the respective subcircuits are composed of nonorthologous regulatory genes.
机译:发育基因调控网络(GRN)的模块化组件或子电路执行特定的发育功能,例如细胞身份的规范。我们调查了此类子电路的示例,并将其结构与相应的开发功能相关联。这些关系超越了生物和基因,如控制果蝇胚胎中皮层规格和海胆中内胚层规格的子回路的类似结构所示,即使各个子回路均由非直系调控基因组成。

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