...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Admixture dynamics in Hispanics: A shift in the nuclear genetic ancestry of a South American population isolate
【24h】

Admixture dynamics in Hispanics: A shift in the nuclear genetic ancestry of a South American population isolate

机译：西班牙裔的混合动力：南美人群分离株的核遗传谱系的转变

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Although it is well established that Hispanics generally have a mixed Native American, African, and European ancestry, the dynamics of admixture at the foundation of Hispanic populations is heterogeneous and poorly documented. Genetic analyses are potentially very informative for probing the early demographic history of these populations. Here we evaluate the genetic structure and admixture dynamics of a province in northwest Colombia (Antioquia), which prior analyses indicate was founded mostly by Spanish men and native women. We examined surname, Y chromosome, and mtDNA diversity in a geographically structured sample of the region and obtained admixture estimates with highly informative autosomal and X chromosome markers. We found evidence of reduced surname diversity and support for the introduction of several common surnames by single founders, consistent with the isolation of Antioquia after the colonial period. Y chromosome and mtDNA data indicate little population substructure among founder Antioquian municipalities. Interestingly, despite a nearly complete Native American mtDNA background, Antioquia has a markedly predominant European ancestry at the autosomal and X chromosome level, which suggests that, after foundation, continuing admixture with Spanish men (but not with native women) increased the European nuclear ancestry of Antioquia. This scenario is consistent with historical information and with results from population genetics theory.
机译：尽管众所周知，拉美裔通常具有混合的美洲原住民，非洲和欧洲血统，但在西班牙裔人口基础上的混合动力是异质的，文献记载也很少。遗传分析对于探查这些人群的早期人口统计学历史可能很有帮助。在这里，我们评估了哥伦比亚西北部（安蒂奥基亚省）的一个省的遗传结构和混合动力，先前的分析表明该省主要由西班牙男性和本地女性建立。我们检查了该地区的地理结构样本中的姓，Y染色体和mtDNA多样性，并获得了具有高度信息化的常染色体和X染色体标记的混合估计。我们发现了减少的姓氏多样性的证据，并支持由单个创建者引入几种常见的姓氏，这与殖民时期之后对安蒂奥基亚的隔离一致。 Y染色体和mtDNA数据表明，创始人安蒂奥基安自治市中的人口子结构很少。有趣的是，尽管近乎完整的美洲原住民mtDNA背景，Antioquia在常染色体和X染色体水平上具有明显的欧洲血统，这表明在建立之后，继续与西班牙男性（而不是与土著女性）混合可以增加欧洲核血统。安蒂奥基亚岛。这种情况与历史信息和人口遗传学理论的结果是一致的。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号