Drusen, choroidal neovascularization, and retinal pigment epithelium dysfunction in SOD1-deficient mice: A model of age-related macular degeneration

著录项

• 来源
  《Proceedings of the National Academy of Sciences of the United States of America》 |2006年第30期|p. 11282-11287|共6页
• 作者

  Imamura Y; Noda S; Hashizume K; Shinoda K; Yamaguchi M; Uchiyama S; Shimizu T; Mizushima Y; Shirasawa T; Tsubota K;

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• 作者单位

  Keio Univ, Sch Med, Dept Ophthalmol, Shinjuku Ku, Tokyo 1608582, Japan;

  Tokai Univ, Sch Hlth Sci, Dept Nursing, Isehara, Kanagawa 2591193, Japan;

  Natl Hosp Org, Tokyo Med Ctr, Natl Inst Sensory Organs, Lab Visual Physiol,Meguro Ku, Tokyo 1528902, Japan;

  Tokyo Metropolitan Inst Gerontol, Res Team Mol Biomarkers, Itabashi Ku, Tokyo 1730015, Japan;

  Jikei Univ, DDS Inst, Sch Med, Minato Ku, Tokyo 1058461, Japan;

  Tokyo Dent Coll, Dept Ophthalmol, Chiba 2728513, Japan;

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• 收录信息 美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
• 原文格式 PDF
• 正文语种 eng
• 中图分类 自然科学总论;
• 关键词

  animal model; superoxide dismutase; MANGANESE SUPEROXIDE-DISMUTASE; CAUSE-SPECIFIC PREVALENCE; FACTOR-H POLYMORPHISM; ANTIOXIDANT ENZYMES; BRUCHS MEMBRANE; OXIDATIVE STRESS; KNOCKOUT MICE; PATHOGENESIS; RISK; CATARACT;

  机译：动物模型;超氧化物歧化酶;超氧化物歧化酶;病因流行;因子H多态性;抗氧化剂酶;面包膜;氧化应激;敲除小鼠;致病性;风险;白内障;