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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Prefrontal cortex and flexible cognitive control: Rules without symbols
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Prefrontal cortex and flexible cognitive control: Rules without symbols

机译:前额叶皮层和灵活的认知控制:无符号规则

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摘要

Human cognitive control is uniquely flexible and has been shown to depend on prefrontal cortex (PFC). But exactly how the biological mechanisms of the PFC support flexible cognitive control remains a profound mystery. Existing theoretical models have posited powerful task-specific PFC representations, but not how these develop. We show how this can occur when a set of PFC-specific neural mechanisms interact with breadth of experience to self organize abstract rule-like PFC representations that support flexible generalization in novel tasks. The same model is shown to apply to benchmark PFC tasks (Stroop and Wisconsin card sorting), accurately simulating the behavior of neurologically intact and frontally damaged people.
机译:人类的认知控制具有独特的灵活性,并且已显示依赖于前额叶皮层(PFC)。但是,PFC的生物学机制究竟如何支持灵活的认知控制仍然是一个深奥的谜。现有的理论模型已经建立了功能强大的特定于任务的PFC表示,但是并没有如何发展它们。我们展示了当一组特定于PFC的神经机制与经验的广度相互作用以自组织抽象的规则式PFC表示形式(在新任务中支持灵活概括)时,如何发生这种情况。该模型已显示适用于基准PFC任务(Stroop和Wisconsin卡分类),可精确模拟神经功能完好和正面受损的人的行为。

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