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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Biography of Zhu Chen
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Biography of Zhu Chen

机译：朱Chen传

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The alchemist's symbol for arsenic is a menacing coiled serpent, and perhaps rightly so. The element of arsenic has certainly earned a great deal of infamy from the reign of the Borgias to the novels of Agatha Christie, and in more recent times as a toxic contaminant of drinking water. But the symbolic serpent also coils around the staff of Aesculapius, an international symbol for medicine; arsenic the poison is also arsenic the healer. Indeed, writing in his Inaugural Article in this issue of PNAS (1) Zhu Chen of the Shanghai Institute of Hematology (Shanghai, China) describes arsenicals as among the oldest drugs known. Chen has been the principal figure behind the development of a radical approach to acute promyelocytic leukemia (APL) that combines the arsenic of traditional Chinese medicine (TCM) with Western medicine. His work in this area has provided a molecular rationale for an effective cancer therapy and led to his election to the National Academy of Sciences in 2003.
机译：炼金术士的砷象征是一个险恶的盘绕蛇，也许是正确的。从波吉亚人的统治到阿加莎·克里斯蒂的小说，砷的元素无疑引起了极大的侮辱，并且在最近一段时间，砷已成为饮用水的有毒污染物。但是象征性的蛇也缠绕在国际医学象征Aesculapius的工作人员身上。砷的毒药也是砷的治疗师。确实，在本期《美国国家科学院院刊》（PNAS）的就职演说中，上海血液学研究所（中国上海）的朱辰将砷描述为已知的最古老的药物之一。陈一直是将急性中性粒细胞白血病（APL）的根本方法发展起来的主要人物，该方法将中药中的砷（TCM）与西药相结合。他在这一领域的工作为有效的癌症治疗提供了分子基础，并导致他于2003年当选为美国国家科学院院士。

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