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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >The unpredictable past of Plasmodium vivax revealed in its genome
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The unpredictable past of Plasmodium vivax revealed in its genome

机译:间日疟原虫的基因组揭示了不可预测的过去

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摘要

Until quite recently, very little information has been avail-able about the genome con-tent and structure of parasitic protozoa. This inadequacy has been rectified by the advent of high-throughput strategies that permit sequencing of whole genomes and enhanced computational capacities that render this information tractable. The current list of complete or near-complete genomes includes some of the greatest scourges of humans and their domesticated companions. Among these miscreants are several members of the genus Plasmodium, the agents of malaria. Scores of species of Plasmodium have been described and comprise pathogens of every major group of terrestrial vertebrates.
机译:直到最近,关于寄生虫原生动物的基因组含量和结构的信息很少。高通量策略的出现纠正了这种不足,该策略允许对整个基因组进行测序,并增强了计算能力,使该信息易于处理。当前完整或接近完整的基因组列表包括一些人类及其家养同伴的最大祸害。在这些不法之徒中,疟原虫是疟原虫的几个成员。已经描述了数十种疟原虫的种类,并且包括陆地脊椎动物的每个主要组的病原体。

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