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首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Directional selection has shaped the oral jaws of Lake Malawi cichlid fishes.
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Directional selection has shaped the oral jaws of Lake Malawi cichlid fishes.

机译:定向选择塑造了马拉维湖丽鱼科鱼类的口腔颌骨。

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摘要

East African cichlid fishes represent one of the most striking examples of rapid and convergent evolutionary radiation among vertebrates. Models of ecological speciation would suggest that functional divergence in feeding morphology has contributed to the origin and maintenance of cichlid species diversity. However, definitive evidence for the action of natural selection has been missing. Here we use quantitative genetics to identify regions of the cichlid genome responsible for functionally important shape differences in the oral jaw apparatus. The consistent direction of effects for individual quantitative trait loci suggest that cichlid jaws and teeth evolved in response to strong, divergent selection. Moreover, several chromosomal regions contain a disproportionate number of quantitative trait loci, indicating a prominent role for pleiotropy or genetic linkage in the divergence of this character complex. Of particular interest are genomic intervals with concerted effects on both the length and height of the lower jaw. Coordinated changes in this area of the oral jaw apparatus are predicted to have direct consequences for the speed and strength of jaw movement. Taken together, our results imply that the rapid and replicative nature of cichlid trophic evolution is the result of directional selection on chromosomal packages that encode functionally linked aspects of the craniofacial skeleton.
机译:东非丽鱼科鱼类是脊椎动物之间迅速而聚合的辐射最显着的例子之一。生态物种形成的模型表明,进食形态的功能差异有助于丽鱼科鱼物种的起源和维持。然而,缺少自然选择作用的确切证据。在这里,我们使用定量遗传学来确定丽鱼科鱼基因组的区域,这些区域负责口腔颌骨装置中功能上重要的形状差异。各个数量性状基因座的一致作用方向表明,丽鱼科鱼的下颚和牙齿是根据强烈而发散的选择而进化的。此外,几个染色体区域包含数量不成比例的数量性状基因座,表明多效性或遗传连锁在此性状复合体的发散中起着重要作用。特别令人感兴趣的是对下颌的长度和高度均具有协同作用的基因组间隔。预计口腔颌骨器械该区域的协调变化将直接影响颌骨运动的速度和强度。综上所述,我们的结果暗示丽鱼科鱼营养进化的快速和可复制性是对染色体包装进行定向选择的结果,该包装编码了颅面骨架的功能性连接方面。

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