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Horizontal gene transfer: A critical view.

机译:水平基因转移:关键观点。

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摘要

It has been suggested that horizontal gene transfer (HGT) is the "essence of phylogeny." In contrast, much data suggest that this is an exaggeration resulting in part from a reliance on inadequate methods to identify HGT events. In addition, the assumption that HGT is a ubiquitous influence throughout evolution is questionable. Instead, rampant global HGT is likely to have been relevant only to primitive genomes. In modern organisms we suggest that both the range and frequencies of HGT are constrained most often by selective barriers. As a consequence those HGT events that do occur most often have little influence on genome phylogeny. Although HGT does occur with important evolutionary consequences, classical Darwinian lineages seem to be the dominant mode of evolution for modern organisms.
机译:已经提出,水平基因转移(HGT)是“系统发育的本质”。相反,许多数据表明这是一种夸张,其部分原因是依赖于识别HGT事件的方法不足。另外,关于HGT在整个进化过程中无处不在的影响的假设值得怀疑。相反,猖global的全球HGT可能只与原始基因组有关。在现代生物中,我们建议HGT的范围和频率都经常受到选择性屏障的限制。结果,那些最常发生的HGT事件对基因组系统发育几乎没有影响。尽管HGT确实会产生重要的进化后果,但经典的达尔文主义谱系似乎是现代生物进化的主要方式。

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