How are the ABC transporters energized?

Hiroshi Nikaido

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How are the ABC transporters energized?

机译：ABC运输车如何通电？

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摘要

ATP-binding cassette (ABC) trans- porters are probably the most com- mon as well as the most wide-spread active transport systems. This family includes many bacterial transporters that either export complex molecules (lipids, polysac- charides, or proteins), or import small nutrients in cooperation with the soluble solute-binding proteins (e.g., the maltose and histidine transport systems of Esche- richia coli), as well as such human proteins as the cystic fibrosis transmembrane con- ductance regulator and the P-glycoprotein that pumps out many anticancer agents.

机译：ATP结合盒（ABC）转运蛋白可能是最常见也是传播最广泛的主动转运系统。这个家族包括许多细菌转运蛋白，它们可以输出复杂的分子（脂质，多糖或蛋白质），或与可溶性溶质结合蛋白协同输入少量营养素（例如，大肠杆菌的麦芽糖和组氨酸转运系统）以及诸如囊性纤维化跨膜电导调节剂和泵出许多抗癌药的P-糖蛋白等人类蛋白质。

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《Proceedings of the National Academy of Sciences of the United States of America》 |2002年第15期|p.9609-9610|共2页
作者
Hiroshi Nikaido;
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收录信息美国《科学引文索引》(SCI);美国《生物学医学文摘》(MEDLINE);美国《化学文摘》(CA);
原文格式 PDF
正文语种 eng
中图分类自然科学总论;
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专利

1. Identification of an ATPase, MsmK, Which Energizes Multiple Carbohydrate ABC Transporters in Streptococcus pneumoniae [J] . Carolyn Marion, Andrew E. Aten, Shireen A. Woodiga, Infection and immunity . 2011,第10期

机译：ATPase MsmK的鉴定，该酶可增强肺炎链球菌中的多种碳水化合物ABC转运蛋白
2. Catalog of 605 single-nucleotide polymorphisms (SNPs) among 13 genes encoding human ATP-binding cassette transporters: ABCA4, ABCA7, ABCA8, ABCD1, ABCD3, ABCD4, ABCE1, ABCF1, ABCG1, ABCG2, ABCG4, ABCG5, and ABCG8. [J] . Iida A, Saito S, Sekine A, Journal of human genetics . 2002,第6期

机译：在编码人ATP结合盒转运蛋白的13个基因中的605个单核苷酸多态性（SNP）的目录：ABCA4，ABCA7，ABCA8，ABCD1，ABCD3，ABCD4，ABCE1，ABCF1，ABCG1，ABCG2，ABCG4，ABCG5和ABCG8。
3. Variation and evolution of the ABC transporter genes ABCB1, ABCC1, ABCG2, ABCG5 and ABCG8: implication for pharmacogenetics and disease. [J] . Silverton L, Dean M, Moitra K Drug metabolism and drug interactions . 2011,第4期

机译：ABC转运蛋白基因ABCB1，ABCC1，ABCG2，ABCG5和ABCG8的变异和进化：对药物遗传学和疾病的影响。
4. Pharmaceutical Surfactants Interact Differently with the Human Efflux Transporters ABCB1 and ABCC2 [C] . Annual meeting exposition of the Controlled Release Society . 2009

机译：药物表面活性剂与人流速转运蛋白ABCB1和ABCC2相互作用
5. Roles of ABCG5 ABCG8 cholesterol transporter in lipid homeostasis. [D] . Wang, Yuhuan. 2015

机译：ABCG5 ABCG8胆固醇转运蛋白在脂质稳态中的作用。
6. Identification of an ATPase MsmK Which Energizes Multiple Carbohydrate ABC Transporters in Streptococcus pneumoniae [O] . Carolyn Marion, Andrew E. Aten, Shireen A. Woodiga, 2011

机译：ATPase MsmK的鉴定该酶可增强肺炎链球菌中的多种碳水化合物ABC转运蛋白
7. Identification of an ATPase, MsmK, Which Energizes Multiple Carbohydrate ABC Transporters in Streptococcus pneumoniae ▿ [O] . Marion, Carolyn, Aten, Andrew E., Woodiga, Shireen A., 2011

机译：ATPase MsmK的鉴定，该酶可激活肺炎链球菌中的多种碳水化合物ABC转运蛋白▿

How are the ABC transporters energized?

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