The potential coding capacity of the hu- man genome is currently a topic of great interest. The number of genes predicted from the recent human-genome analysis was at the lower end of previous estimates, which had ranged between about 30,000 and 120,000 (1,2). Whereas estimates of gene number are likely to increase based on ad- ditional experimental evidence and im- proved gene-finding algorithms, it is clear that gene number is only one mechanism for creating the genetic diversity required to encode the full complement of human pro- teins.
展开▼
