...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Proceedings of the National Academy of Sciences of the United States of America >Quantitative assessment of Hox complex expression in the indirect development of the polychaete annelid Chaetopterus sp.
【24h】

Quantitative assessment of Hox complex expression in the indirect development of the polychaete annelid Chaetopterus sp.

机译：定量评估多壳anAnelid Chaetopterus sp。间接发展中的Hox复合物表达。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

A prediction from the set-aside theory of bilaterian origins is that pattern formation processes such as those controlled by the Hox cluster genes are required specifically for adult body plan forma- tion. This prediction can be tested in animals that use maximal indirect development. in which the embryonic formation of the larva and the postembryonic formation of the adult body plan are temporally and spatially distinct. To this end, we quantitatively measured the amount of transcripts for five Hox genes in embryos of a lophotrochozoan, the polychaete annelid Chaetopterus sp. The polychaete Hox complex is shown not to be expressed during embryogenesis, but transcripts of all measured Hox complex genes are detected at significant levels during the initial stages of adult body plan formation. Temporal colinearity in the sequence of their activation is observed, so that activation follows the 3'--5' arrange- ment of the genes. Moreover, Hox gene expression is spatially localized to the region of teloblastic set-aside cells of the later- stage embryos. This study shows that an indirectly developing lophotrochozoan shares with an indirectly developing deuteros- tome, the sea urchin, a common mode of Hox complex utilization: construction of the larva, whether a trochophore or dipleurula, does not involve Hox cluster expression. but in both forms the complex is expressed in the set-aside cells from which the adult body plan derives.
机译：搁浅的双语者起源理论预测，成年人体计划的形成特别需要图案形成过程，例如受Hox簇基因控制的那些过程。可以在使用最大间接发育的动物中检验这一预测。其中幼虫的胚胎形成和成年人体计划的胚后形成在时间和空间上是不同的。为此，我们定量测量了恶风虫（Polychaete annelid Chaetopterus sp。）胚胎中五个Hox基因的转录本数量。该多毛类Hox复合物在胚胎发生过程中未表达，但在成年人体计划形成的初始阶段，所有测得的Hox复合物基因的转录本均以显着水平被检测到。观察到它们激活序列的时间共线性，因此激活遵循基因的3'-5'排列。此外，Hox基因表达在空间上位于后期胚胎的成核细胞搁置细胞区域。这项研究表明，间接发展的滋养体与间接发展的氘核海胆共享海胆，这是Hox复合体利用的一种常见方式：幼虫的构建，无论是滋养体还是胸膜膜，均不涉及Hox簇的表达。但是这两种形式的复合物都在成年人体计划产生的预留细胞中表达。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号