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首页> 外文期刊>Progress in Natural Science >A novel DNA computing model based on RecA-mediated triple-stranded DNA structure
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A novel DNA computing model based on RecA-mediated triple-stranded DNA structure

机译:基于RecA介导的三链DNA结构的新型DNA计算模型

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摘要

The field of DNA computing emerged in 1994 after Adleman's paper was published. Henceforth, a few scholars solved some noted NP-complete problems in this way. And all these methods of DNA computing are based on conventional Watson-Crick hydrogen bond of doublehelical DNA molecule. In this paper, we show that the triple-stranded DNA structure mediated by RecA protein can be used for solving computational problems. Sequence-specific recognition of double-stranded DNA by oligonucleotide-directed triple helix (triplex) formation is used to carry out the algorithm. We present procedure for the 3-vertex-colorability problems. In our proposed procedure, it is suggested that it is possible to solve more complicated problems with more variables by this model.
机译:DNA计算领域于1994年在Adleman的论文发表后出现。此后,一些学者以这种方式解决了一些著名的NP完全问题。而所有这些DNA计算方法均基于双螺旋DNA分子的常规Watson-Crick氢键。在本文中,我们表明,RecA蛋白介导的三链DNA结构可用于解决计算问题。通过寡核苷酸定向的三重螺旋(triplex)形成对双链DNA的序列特异性识别被用于执行该算法。我们提出了3-vertex-colorability问题的程序。在我们提出的过程中,建议通过该模型解决具有更多变量的更复杂问题。

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