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Palliation and Chronic Renal Failure: Opioid and Other Palliative Medications - Dosage Guidelines

机译:姑息和慢性肾衰竭:阿片类药物和其他姑息药物-剂量指南

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摘要

Palliation of symptoms is important in a variety of conditions, both malignant and non-malignant. These symptoms can be present in patients with chronic renal failure that may, or may not, require dialysis. In this review, a table of data is presented outlining the information known about the drugs and suggested alterations to both dosage or dose interval in renal failure and dialysis. Important changes are also discussed. It is also clear from the table presented that there are multiple medications where the interaction of renal failure or dialysis is not known. Caution may be necessary to avoid the development of toxicity from those medications or their metabolites.
机译:在恶性和非恶性的各种情况下,症状的缓解都很重要。这些症状可能出现在可能需要或不需要透析的慢性肾功能衰竭患者中。在这篇综述中,提供了一份数据表,概述了有关药物的已知信息,并建议了肾衰竭和透析中剂量或剂量间隔的改变。还讨论了重要的更改。从所提供的表格中还可以清楚地看到,存在多种药物,其中肾功能衰竭或透析的相互作用尚不清楚。为避免这些药物或其代谢产物产生毒性,可能需要谨慎行事。

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