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Just around the corner: rhetorics of progress and promise in genetic research

机译：指日可待：基因研究取得进步和希望的言论

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摘要

The emerging "diabetes epidemic" threatens to affect 366 million people worldwide by 2030. In the UK, almost 2 million people (about 3.9 percent of the population) are currently diagnosed with diabetes and it is estimated that a further 1 million people have the disease but do not realize it. The prevalence of diabetes, its complications and their effects on the lives of those living with diabetes mean that diabetes research has the potential to bring significant benefits. In this paper, we are concerned with the research involving human embryonic stem (HES) cells that sees diabetes as a potential therapeutic location. Drawing on the idea of the "certainty trough" we examine how the hopes and uncertainties associated with this complex research agenda are understood. We show that those at the research front and those most opposed to the research agenda appear to be the most aware of the uncertainties that need to be resolved. In contrast, funders, typically one-step removed from the research work, see the promise of the research as more real and more likely to be achieved. Significantly, these optimistic funders are supported in their beliefs by the research scientists as constitutive claims are reproduced within the contingent forum. The effect is a collaborative project in which the promise of a technical solution "just around the corner" is sustained whilst concerns about the future difficulties are marginalized.
机译：到2030年，正在出现的“糖尿病流行病”可能会影响全球3.66亿人。在英国，目前有将近200万人（约占人口的3.9％）被诊断出患有糖尿病，据估计还有100万人患有糖尿病但没有意识到。糖尿病的流行，其并发症及其对糖尿病患者生命的影响意味着，糖尿病研究具有带来巨大益处的潜力。在本文中，我们关注涉及人类胚胎干（HES）细胞的研究，该研究将糖尿病视为潜在的治疗手段。借助“确定性低谷”的思想，我们研究了如何理解与这一复杂的研究议程相关的希望和不确定性。我们表明，处于研究前沿和最反对研究议程的人们似乎最了解需要解决的不确定性。相比之下，出资者通常将研究工作从第一步中走了一步，他们认为研究的希望更加真实，并且更有可能实现。值得一提的是，这些乐观的资助者的信念得到了研究科学家的支持，因为在临时性论坛中复制了本能主张。效果是一个协作项目，其中“迫在眉睫”的技术解决方案的承诺得以维持，而对未来困难的担忧却被边缘化了。

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  • 来源
    《Public understanding of science》 |2009年第1期|43-59|共17页
  • 作者

    Robert Evans; Inna Kotchetkova; Susanne Langer;

  • 作者单位

    Glamorgan Building, King Edward VII Avenue, Cardiff, CF10 3WT, UK;

    National Centre for Research Methods at Cardiff University;

    Cardiff University-based qualita-tive methods node (QUALITI) of the ESRC National Centre for Research Methods;

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