...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Radiation and Environmental Biophysics >Thyroid cancer incidence in Ukraine: trends with reference to the Chernobyl accident
【24h】

Thyroid cancer incidence in Ukraine: trends with reference to the Chernobyl accident

机译：乌克兰甲状腺癌的发病率：切尔诺贝利事故的趋势

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

For the first time, a comparative analysis of thyroid cancer incidence in Ukraine after the Chernobyl accident was done in a cohort that is almost as large as the general population. On the basis of thyroid doses from radioactive iodine in individuals aged 1–18 years at the time of accident, geographic regions of Ukraine with low and high average accumulated thyroid doses were established and designated “low-exposure” and “high-exposure” territories, respectively. A significant difference of thyroid cancer incidence rates as a function of time between the two territories was found. That is, the increase in the incidence was higher in high-exposure regions than in low-exposure regions. The incidence rates varied substantially among the different attained age-groups, especially in the youngest one (up to 19 years old). The analysis that was adjusted for screening and technological effects also indicated that in the high-exposure regions, thyroid cancer incidence rates at the age of diagnosis of 5–9, 10–14 and 15–19 years were significantly higher in those born in 1982–1986 compared to those born in 1987–1991, while in the low-exposure regions, no significant difference was observed. The observed probable excess of radiation-induced thyroid cancer cases in adults exposed to radioactive iodine from the Chernobyl accident, especially in females, may be due to the high power of the present study. However, it should be noted that our investigation was not essentially free from ecological biases.
机译：首次在切尔诺贝利事故后对乌克兰甲状腺癌的发病率进行了比较分析，该队列几乎与普通人群一样多。根据事故发生时年龄为1-18岁的个体中放射性碘的甲状腺剂量，确定了乌克兰平均甲状腺累积剂量低和高的地理区域，并将其指定为“低暴露”和“高暴露”地区， 分别。发现这两个地区之间的甲状腺癌发病率随时间呈显着差异。即，高曝光区域的发生率的增加高于低曝光区域的发生率。在不同的年龄组中，发病率差异很大，尤其是在最小的年龄组（不超过19岁）中。根据筛查和技术效果进行调整后的分析还表明，在1982年出生的人群中，在高暴露地区，诊断为5-9岁，10-14岁和15-19岁的甲状腺癌发病率显着更高。与1987年至1991年出生的婴儿相比，1986年为婴儿，而在低暴露地区，则没有显着差异。在切尔诺贝利事故中暴露于放射性碘的成人中，尤其是在女性中，观察到的放射性诱发的甲状腺癌病例可能过量，这可能是由于本研究的强大功效。但是，应该指出的是，我们的调查基本上没有生态偏差。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号