首页> 外文期刊>Radiation Protection Dosimetry >APPLICATION OF REFLECTANCE CONFOCAL MICROSCOPY FOR EARLY DIAGNOSIS OF RADIATION-INDUCED ACUTE DERMATITIS IN RADIOSENSITIVE PATIENT: CASE STUDY
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APPLICATION OF REFLECTANCE CONFOCAL MICROSCOPY FOR EARLY DIAGNOSIS OF RADIATION-INDUCED ACUTE DERMATITIS IN RADIOSENSITIVE PATIENT: CASE STUDY

机译:反射共聚焦显微镜在放射敏感性患者辐射诱发的急性皮炎早期诊断中的应用:案例研究

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摘要

According to the guidelines on cancer treatment up to 52% of newly diagnosed cancer patients should be treated with external beam radiotherapy. Ionizing radiation (IR)-induced skin injury (radiation dermatitis) occurs in up to 95% of radiotherapy patients and can manifest from mild erythema till necrosis and ulceration. Individual radiosensitivity was proposed to be an important factor for the development of adverse reactions to IR. Therefore, assessment of radiosensitivity could be useful in predicting and dealing with radiation injuries caused by both radiotherapy and accidental overexposure. Here, we present a case of early diagnosis of IR-induced skin lesions performed by reflectance confocal microscopy in comparison to clinical evaluation in a highly radiosensitive patient.
机译:根据癌症治疗指南,新诊断的癌症患者中多达52%应当接受外部束放射治疗。高达95%的放射治疗患者会发生电离辐射(IR)引起的皮肤损伤(辐射性皮炎),并且可表现为轻度红斑直至坏死和溃疡。有人提出个人放射敏感性是发展对IR不良反应的重要因素。因此,放射敏感性的评估可能对预测和处理由放射治疗和意外过度暴露引起的放射损伤有用。在这里,我们提出了一个与辐射敏感性高的患者的临床评估相比,通过反射共聚焦显微镜对IR诱发的皮肤病变进行早期诊断的案例。

著录项

  • 来源
    《Radiation Protection Dosimetry》 |2018年第1期|93-97|共5页
  • 作者单位

    Vilnius Univ, Dept Neurobiol & Biophys, LT-10257 Vilnius, Lithuania;

    Natl Canc Inst, Biomed Phys Lab, LT-08660 Vilnius, Lithuania;

    Natl Canc Inst, Dept Radiat Oncol, LT-08660 Vilnius, Lithuania;

    Natl Canc Inst, Med Phys Dept, LT-08660 Vilnius, Lithuania;

    Radiat Protect Ctr, LT-08221 Vilnius, Lithuania;

  • 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
  • 中图分类
  • 关键词

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