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首页> 外文期刊>Radiation Protection Dosimetry >CELLULAR DOSE DISTRIBUTIONS OF INHALED RADON PROGENY AMONG DIFFERENT LOBES OF THE HUMAN LUNG
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CELLULAR DOSE DISTRIBUTIONS OF INHALED RADON PROGENY AMONG DIFFERENT LOBES OF THE HUMAN LUNG

机译：一种人肺不同叶片吸入氡后代的细胞剂量分布

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摘要

Basal and secretory cell doses in the different lobes of the human lung following inhalation of short-lived radon progeny were calculated for a five-lobe asymmetric, stochastic lung model, considering the non-uniform ventilation of the lobes. Dose calculations for defined exposure conditions revealed that the upper lobes receive higher doses than the average bronchial dose for the whole lung, with the right upper lobe receiving the highest dose. The resulting inter-lobar distribution of cellular bronchial doses indicated that the non-uniform lung morphometry is the dominating factor, while non-uniform ventilation only slightly enhances the lobar differences. The comparison of average lobe-specific bronchial doses with the average bronchial dose for the whole lung allows the calculation of lobe-specific dose weighting factors, which can be used to convert average bronchial doses based on symmetric airway generation or bronchial compartment models to lobar bronchial doses.
机译：考虑到裂片的不均匀通风，计算了在吸入短寿命的氡后代后的人肺的基础和分泌细胞剂量。定义的暴露条件的剂量计算显示，上瓣比整肺的平均支气管剂量较高，右上叶接收最高剂量。所得到的细胞支气管剂量的洛洛达间分布表明，非均匀的肺形式是主导因子，而非均匀通风仅略微增强瓣多巴差异。全肺平均支气管剂量平均支气管剂量的比较允许计算叶特异性剂量加权因子，可用于将平均支气管剂量转化为对称气道代或支气管室模型转换为Lobar支气管剂量。

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  • 来源
    《Radiation Protection Dosimetry》 |2020年第4期|444-463|共20页
  • 作者

    Werner Hofmann; Renate Winkler-Heil;

  • 作者单位

    Biological Physics Group Department of Chemistry and Physics of Materials University of Salzburg Hellbrunner Str. 34 5020 Salzburg Austria;

    Biological Physics Group Department of Chemistry and Physics of Materials University of Salzburg Hellbrunner Str. 34 5020 Salzburg Austria;

  • 收录信息 美国《科学引文索引》(SCI);美国《化学文摘》(CA);
  • 原文格式 PDF
  • 正文语种 eng
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